SELENOT: A Protein Involved in Homeostasis and Signaling Pathways

Target Name: SELENOT

NCBI ID: G51714

SELENOT

SELENOT: A Protein Involved in Homeostasis and Signaling Pathways

SELENOT (Thioredoxin reductase-like selenoprotein T) is a protein that is expressed in various tissues throughout the body, including the liver, heart, and kidneys. It is a member of the thioredoxin gene family, which encodes proteins involved in the detoxification of environmental toxins and other substances. SELENOT is a 21-kDa protein that is composed of 21 amino acid residues.

SELENOT is involved in a number of cellular processes that are important for maintaining cellular homeostasis. It plays a role in the detoxification of xenobiotics, such as those that are harmful to the body. Xenobiotics can cause damage to cells and contribute to a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. SELENOT is involved in the detoxification of these xenobiotics, which helps to protect the body against their harmful effects.

SELENOT is also involved in the regulation of cellular signaling pathways. It has been shown to play a role in the signaling pathway that is responsible for the regulation of cell proliferation and differentiation. This pathway is important for the development and maintenance of tissues and organs, and it is thought to be involved in the development of many diseases, including cancer. SELENOT may be a drug target (or biomarker) that can be targeted by small molecules or other therapeutic agents in order to disrupt its functions and prevent the development of these diseases.

SELENOT is also involved in the regulation of cellular transport processes. It is a transmembrane protein that is involved in the transport of a variety of molecules, including ions, proteins, and other substances across the cell membrane. This function is important for the regulation of cellular homeostasis and for the proper functioning of many cellular processes.

SELENOT is also involved in the regulation of cellular signaling pathways that are involved in inflammation and immune response. It has been shown to play a role in the regulation of inflammation and in the development of inflammatory diseases. SELENOT may be a drug target (or biomarker) that can be targeted by small molecules or other therapeutic agents in order to disrupt its functions and prevent the development of these diseases.

In conclusion, SELENOT (Thioredoxin reductase-like selenoprotein T) is a protein that is involved in a variety of cellular processes that are important for maintaining cellular homeostasis and for the regulation of cellular signaling pathways. It may be a drug target (or biomarker) that can be targeted by small molecules or other therapeutic agents in order to disrupt its functions and prevent the development of many diseases. Further research is needed to fully understand the functions of SELENOT and its potential as a drug target.

Protein Name: Selenoprotein T

Functions: Selenoprotein with thioredoxin reductase-like oxidoreductase activity (By similarity). Protects dopaminergic neurons against oxidative stress and cell death (PubMed:26866473). Involved in ADCYAP1/PACAP-induced calcium mobilization and neuroendocrine secretion (By similarity). Plays a role in fibroblast anchorage and redox regulation (By similarity). In gastric smooth muscle, modulates the contraction processes through the regulation of calcium release and MYLK activation (By similarity). In pancreatic islets, involved in the control of glucose homeostasis, contributes to prolonged ADCYAP1/PACAP-induced insulin secretion (By similarity)

The "SELENOT Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SELENOT comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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