GRAMD1C: A Promising Drug Target / Biomarker (G54762)

Target Name: GRAMD1C

NCBI ID: G54762

GRAMD1C

GRAMD1C: A Promising Drug Target / Biomarker

Grammd1c is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key regulator of cell signaling and has been implicated in a number of diseases, including neurodegenerative disorders, autoimmune diseases, and cancer. While a great deal has been learned about Grammd1c and its functions, it remains a highly validated drug target and a promising biomarker for a variety of diseases.

Grammd1c and its functions
Grammd1c is a member of the GRAM family of proteins, which are known for their roles in intracellular signaling. The GRAM family includes a number of different proteins, including Grammd2, Grammd3, and Grammd4, which are involved in a variety of cellular processes, including cell signaling, cytoskeletal organization, and stress response.

One of the key functions of Grammd1c is its role in regulating the activity of intracellular signaling pathways. These pathways are the complex networks of chemical signals that are used by cells to communicate with one another and to control the cell's behavior. Grammd1c is involved in a number of these pathways, including the TGF-β pathway, the PI3K pathway, and the NF-kappa-B pathway.

The TGF-β pathway is a well-known signaling pathway that is involved in a variety of cellular processes, including cell growth, differentiation, and inflammation. The TGF-β pathway is activated by the protein transforming growth factor (TGF), which is a potent regulator of cell signaling. TGF is produced by the liver and is involved in the development and maintenance of tissues, including muscles, bones, and tissues.

Grammd1c is involved in the regulation of TGF-β activity, as well as the development of tissues. It has been shown to play a key role in the development and maintenance of the brain, including the formation of new neurons and the regulation of neurotransmitter release. In addition, Grammd1c has been shown to play a role in the regulation of the immune system, including the development and maintenance of immune cells and the regulation of immune response.

The PI3K pathway is a signaling pathway that is involved in the regulation of cell signaling, including the regulation of growth, differentiation, and inflammation. The PI3K pathway is activated by the protein PI3K, which is a protein that is involved in the production of phospholipids, which are the major components of cell membranes.

Grammd1c is involved in the regulation of PI3K activity, as well as the regulation of cellular signaling. It has been shown to play a key role in the regulation of the production and distribution of phospholipids, which are important for the structure and function of cell membranes. In addition, Grammd1c has been shown to play a role in the regulation of cellular signaling, including the regulation of the production and distribution of signaling proteins.

The NF-kappa-B pathway is a signaling pathway that is involved in the regulation of inflammation, including the regulation of pain perception and the regulation of immune response. The NF-kappa-B pathway is activated by the protein NF-kappa-B, which is a protein that is involved in the production of a variety of signaling proteins.

Grammd1c is involved in the regulation of NF-kappa-B activity, as well as the regulation of cellular signaling. It has been shown to play a key role in the regulation of the production and distribution of signaling proteins, including the production and regulation of neurotransmitters. In addition, Grammd1c has been shown to play

Protein Name: GRAM Domain Containing 1C

Functions: Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (By similarity). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER (By similarity). Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol (By similarity). In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol in the PM is recruited to the endoplasmic reticulum-plasma membrane contact sites (EPCS) which is mediated by the GRAM domain (By similarity). At the EPCS, the sterol-binding VASt/ASTER domain binds to the cholesterol in the PM and facilitates its transfer from the PM to ER (By similarity)

The "GRAMD1C Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GRAMD1C comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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