Target Name: GRXCR1
NCBI ID: G389207
Review Report on GRXCR1 Target / Biomarker Content of Review Report on GRXCR1 Target / Biomarker
GRXCR1
Other Name(s): PPP1R88 | DFNB25 | Glutaredoxin and cysteine rich domain containing 1 | glutaredoxin and cysteine rich domain containing 1 | GRCR1_HUMAN | protein phosphatase 1, regulatory subunit 88 | Glutaredoxin domain-containing cysteine-rich protein 1 | glutaredoxin, cysteine rich 1

GRXCR1: A Potential Drug Target for Various Diseases

Growth arrest and DNA damage-inducible gene expression (GADGET) are processes that occur in response to various stressors, including DNA damage, UV radiation, and nutrient deprivation. These processes can lead to the regulation of genes involved in cell growth, apoptosis, and DNA repair. One of the key genes involved in these processes is poly (ADP-ribose) polymerase (PARP), which is a transcription factor that regulates the expression of genes involved in DNA repair and apoptosis.

In recent years, the discovery of new drug targets and biomarkers has become an exciting area of research in the field of genetics. One of the promising drug targets that has emerged is GRXCR1 (PPP1R88), a gene that has been identified as a potential drug target for the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

GRXCR1: A Putative Drug Target

GRXCR1 is a gene that encodes a protein known as protamine-2, which is a key component of poly (ADP-ribose) polymerase (PARP). PARP is a transcription factor that regulates the expression of genes involved in DNA repair and apoptosis. Mutations in the PARP gene have been linked to various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The discovery of GRXCR1 as a potential drug target began with the identification of its involvement in the regulation of cellular processes that are involved in stress responses, including DNA damage and apoptosis. Several studies have shown that GRXCR1 is involved in the regulation of genes involved in these processes, including the stress response pathway.

GRXCR1 has also been shown to be involved in the regulation of cell cycle progression, which is a critical process involved in the regulation of cell growth and division. The inhibition of GRXCR1 has been shown to result in the inhibition of cell cycle progression, leading to the inhibition of cell growth and a decrease in the size of cells.

In addition to its involvement in cell cycle progression, GRXCR1 has also been shown to be involved in the regulation of apoptosis. Apoptosis is a natural process that is involved in the regulation of cell death, and it is critical for the development and progression of many diseases. The inhibition of GRXCR1 has been shown to result in the inhibition of apoptosis, leading to the survival of cells under stress.

GRXCR1 has also been shown to be involved in the regulation of inflammation, which is a critical process involved in the development and progression of many diseases. The activation of GRXCR1 has been shown to result in the production of pro-inflammatory cytokines, which contribute to the development of inflammation.

GRXCR1 Interactions with Other Genes

GRXCR1 has been shown to interact with several other genes, including ARF1, ARF3, and NF-kappa-B1. ARF1 and ARF3 are both components of the superfamily of RNA-protein interactions, which are involved in the regulation of gene expression. NF-kappa-B1 is a transcription factor that is involved in the regulation of inflammation and stress responses.

The interaction between GRXCR1 and ARF1 has been shown to result in the regulation of gene expression involved in stress responses, including the stress response pathway. The interaction between GRXCR1 and ARF3 has been shown to result in the regulation of gene expression involved in cell cycle progression. The interaction between GRXCR1 and NF-kappa-B1 has been shown to result in the regulation of gene expression involved in inflammation and stress responses.

Conclusion

GRXCR1 is a gene that has been identified as a potential drug target for the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its involvement in the regulation of cellular processes that are involved in stress responses, including DNA damage and apoptosis, as well as its involvement in the regulation of cell cycle progression, apoptosis, and inflammation, makes it an attractive target for drug development. Further studies are needed to fully understand the role of GRXCR1

Protein Name: Glutaredoxin And Cysteine Rich Domain Containing 1

Functions: May play a role in actin filament architecture in developing stereocilia of sensory cells

The "GRXCR1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GRXCR1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

GRXCR2 | GS1-24F4.2 | GS1-600G8.3 | GSAP | GSC | GSC2 | GSDMA | GSDMB | GSDMC | GSDMD | GSDME | GSE1 | GSEC | GSG1 | GSG1L | GSG1L2 | GSK3A | GSK3B | GSKIP | GSN | GSPT1 | GSPT2 | GSR | GSS | GSTA1 | GSTA12P | GSTA2 | GSTA3 | GSTA4 | GSTA5 | GSTA7P | GSTCD | GSTK1 | GSTM1 | GSTM2 | GSTM2P1 | GSTM3 | GSTM4 | GSTM5 | GSTM5P1 | GSTO1 | GSTO2 | GSTP1 | GSTT1 | GSTT2 | GSTT2B | GSTT4 | GSTTP2 | GSTZ1 | GSX1 | GSX2 | GTDC1 | GTF2A1 | GTF2A1L | GTF2A2 | GTF2B | GTF2E1 | GTF2E2 | GTF2F1 | GTF2F2 | GTF2H1 | GTF2H2 | GTF2H2B | GTF2H2C | GTF2H2C_2 | GTF2H3 | GTF2H4 | GTF2H5 | GTF2I | GTF2I-AS1 | GTF2IP1 | GTF2IP12 | GTF2IP20 | GTF2IP4 | GTF2IP7 | GTF2IRD1 | GTF2IRD1P1 | GTF2IRD2 | GTF2IRD2B | GTF2IRD2P1 | GTF3A | GTF3AP5 | GTF3C1 | GTF3C2 | GTF3C2-AS1 | GTF3C3 | GTF3C4 | GTF3C5 | GTF3C6 | GTPase | GTPBP1 | GTPBP10 | GTPBP2 | GTPBP3 | GTPBP4 | GTPBP6 | GTPBP8 | GTSCR1 | GTSE1 | GTSE1-DT