Target Name: GSDMC
NCBI ID: G56169
Review Report on GSDMC Target / Biomarker Content of Review Report on GSDMC Target / Biomarker
GSDMC
Other Name(s): gasdermin C | Melanoma-derived leucine zipper-containing extranuclear factor | Melanoma-derived leucine zipper, extra-nuclear factor | Gasdermin-C | GSDMC-NT | melanoma-derived leucine zipper-containing extranuclear factor | melanoma-derived leucine zipper, extra-nuclear factor | MLZE | GSDMC-CT | GSDMC_HUMAN | Gasdermin-C, N-terminal | Gasdermin-C, C-terminal | Gasdermin C

GSDMC: A Protein Involved in Cellular Processes That Maintain Health

GSDMC, or gasdermin C, is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a key player in the regulation of mitochondrial function and has been linked to a number of cellular processes that are important for maintaining cellular health.

Recent studies have identified GSDMC as a potential drug target for a number of conditions, including neurodegenerative diseases, cardiovascular disease, and renal disease. This is because GSDMC has been shown to play a role in the pathophysiology of these conditions, and may be a useful indicator of disease severity or response to treatment.

One of the key mechanisms by which GSDMC is involved in these processes is its role in the regulation of mitochondrial function. Mitochondria are organelles that are responsible for generating the energy that cells require for their basic life functions, and they are essential for the survival of Almost all living organisms. GSDMC is involved in the regulation of mitochondrial fusion, which is the process by which mitochondria fuse with each other to form a single mitochondrial organelle.

In neurodegenerative diseases, such as Alzheimer's disease, GSDMC has been shown to be involved in the misfolding of proteins, which can lead to the formation of toxic aggregates that are thought to contribute to the progression of the disease. By targeting GSDMC, researchers may be able to develop new treatments for neurodegenerative diseases.

GSDMC is also involved in the regulation of cellular signaling pathways that are important for maintaining cellular health. For example, GSDMC has been shown to be involved in the regulation of the production of reactive oxygen species (ROS), which are molecules that can damage cellular components and contribute to a number of diseases, including cancer and neurodegenerative diseases.

In addition to its role in cellular signaling pathways, GSDMC is also involved in the regulation of mitochondrial dynamics. This is the movement of mitochondria from the cytoplasm to the mitochondrial membrane, where they can interact with other cellular components and carry out their functions. By Regulating the movement of mitochondria, GSDMC may be able to contribute to the proper functioning of these organelles.

GSDMC has also been shown to play a role in the regulation of cellular processes that are important for maintaining tissue repair and regeneration. For example, GSDMC has been shown to be involved in the regulation of the production of cell-cycle proteins, which are proteins that are involved in the process of cell division.

In addition to its role in cellular signaling pathways and mitochondrial function, GSDMC has also been shown to play a role in the regulation of cellular adhesion. This is the process by which cells stick together to form tissues and organs, and is important for the development and maintenance of these structures.

GSDMC has also been shown to play a role in the regulation of cellular processes that are important for the development and maintenance of the blood-brain barrier. The blood-brain barrier is a barrier that separates the brain from the bloodstream, and helps to protect the brain from the harmful effects of drugs and other substances that could be harmful to the brain. GSDMC has been shown to be involved in the regulation of the formation of the blood-brain barrier, which may be an important target for new treatments for neurological disorders.

In conclusion, GSDMC is a protein that is involved in a number of cellular processes that are important for maintaining cellular health. Its role in the regulation of mitochondrial function, cellular signaling pathways, and tissue repair and regeneration makes it an attractive target for new treatments for a variety of conditions. As research continues to advance, it is likely that the role of GSDMC in these processes will be discovered

Protein Name: Gasdermin C

Functions: This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-C, N-terminal) binds to membranes and forms pores, triggering cell death

The "GSDMC Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GSDMC comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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