GSC2: A Potential Drug Target and Biomarker for Homeobox Proteins

Target Name: GSC2

NCBI ID: G2928

GSC2

GSC2: A Potential Drug Target and Biomarker for Homeobox Proteins

Introduction

The study of homeobox genes (HBXs) and their associated proteins has revolutionized our understanding of gene function and the development of new therapeutic approaches. One family of proteins that have garnered significant attention in the study of HBXs is the goosecoid-like (GCX) proteins . GSC2, a member of the GCX family, has been identified as a potential drug target and biomarker for a variety of human diseases.

GSC2: Structure and Function

The GCX family of proteins consists of six members, including GSC1, GSC2, GSC3, GSC4, GSC5, and GSC6. GSC2 is a 21-kDa protein that is expressed in various tissues, including muscle, pancreas, and heart. It has a unique N-terminal region that consists of a 25 amino acid residue sequence known as N-terminal alpha helix.

Like many other proteins, GSC2 plays multiple biological functions within cells. For example, GSC2 can bind to RNA and participate in the regulation of gene expression. It can also participate in cell signal transduction processes, such as regulating gene expression by phosphorylating the promoter of a gene. In addition, GSC2 also has calcium ion storage capacity and is involved in many physiological processes within cells, such as muscle contraction and cell proliferation.

as a drug target

The potential of GSC2 as a drug target has been widely recognized. Since GSC2 is expressed in a variety of cancers, it is considered a promising target for cancer treatment. For example, the association of GSC2 with lung, colorectal, and pancreatic cancers has been supported by several studies.

as biomarker

GSC2 also has potential as a potential biomarker. Since the expression pattern of GSC2 in various cancers is closely related to tumor growth and invasion, it can be used to monitor the condition and treatment effects of tumor patients. In addition, since GSC2 can be expressed as a fluorescent probe, this property can be exploited for highly sensitive detection and treatment of cancer.

Summarize

GSC2 is a drug target and biomarker with great potential. By deeply studying the function of GSC2 in cell biology, we can reveal its important role in treating cancer and provide more effective treatments for cancer patients.

Protein Name: Goosecoid Homeobox 2

Functions: May have a role in development. May regulate its own transcription. May bind the bicoid consensus sequence TAATCC

The "GSC2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GSC2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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