Target Name: GRIK5
NCBI ID: G2901
Review Report on GRIK5 Target / Biomarker Content of Review Report on GRIK5 Target / Biomarker
GRIK5
Other Name(s): Glutamate receptor ionotropic, kainate 5 | GRIK5_HUMAN | Glutamate receptor KA2 | glutamate receptor ionotropic, kainate 5 | KA2 | Glutamate ionotropic receptor kainate type subunit 5, transcript variant 1 | glutamate receptor KA2 | Excitatory amino acid receptor 2 | putative NMDtranscript(altDon_e2) | Glutamate receptor ionotropic, kainate 5 (isoform 1) | excitatory amino acid receptor 2 | GluK5 | glutamate ionotropic receptor kainate type subunit 5 | putative NMDtranscript(del_e13-e15) | Glutamate receptor KA-2 | EAA2 | Glutamate receptor ionotropic kainate 5 | GRIK5 variant 1 | GRIK2

GRIK5: Key Regulator of Brain Neurotransmitters

GRIK5, or Glutamate Receptor Ionotropic, Kainate 5, is a protein that is expressed in the brain and plays a crucial role in neurotransmitter function. It is a member of the G protein-coupled receptor (GPCR) family, which is a large family of transmembrane proteins that play a central role in cellular signaling. GRIK5 is known for its role in synaptic plasticity, which is the ability of the brain to change and adapt over time.

GRIK5 is a key regulator of synaptic plasticity, and it is involved in the formation of new neural connections and the modulation of existing connections. It is thought to play a key role in the regulation of learning and memory, as well as in the development and progression of neurological disorders.

One of the key functions of GRIK5 is its role in modulating the levels of neurotransmitters, such as glutamate, in the brain. Glutamate is a highly life-safe neurotransmitter that is involved in a wide range of brain functions, including learning, memory, and synaptic plasticity. The levels of glutamate in the brain are critical for the proper functioning of the nervous system, and changes in glutamate levels can have a significant impact on brain function.

GRIK5 is known for its ability to regulate the levels of glutamate in the brain by binding to its receptor on the surface of neurons. This receptor is known as the N-methyl-D-aspartate (NMDA) receptor, and it is a key regulator of synaptic plasticity. The binding of GRIK5 to the NMDA receptor allows it to modulate the levels of glutamate in the brain, which can have a significant impact on the functioning of the brain.

In addition to its role in modulating glutamate levels, GRIK5 is also involved in the regulation of other neurotransmitters, including dopamine and GABA. It is thought to play a key role in the regulation of neurotransmitter release and uptake, as well as in the modulation of neurotransmitter interacts with its downstream targets.

GRIK5 is also involved in the regulation of ion channels in the brain, which are responsible for the flow of electrical current through the brain. The regulation of ion channels is an important part of neurotransmission, and changes in ion channel levels can have a significant impact on the functioning of the brain. GRIK5 is thought to play a key role in the regulation of ion channel levels, including the regulation of neurotransmitter release and the modulation of neurotransmitter interactions with its downstream targets.

GRIK5 is also involved in the regulation of protein synthesis, which is the process by which the brain creates new proteins. The regulation of protein synthesis is an important part of neuro development and regulation, and changes in protein synthesis levels can have a significant impact on the functioning of the brain. GRIK5 is thought to play a key role in the regulation of protein synthesis, including the regulation of neurotransmitter release and the modulation of neurotransmitter interactions with its downstream targets.

In conclusion, GRIK5 is a protein that is involved in the regulation of a wide range of neurotransmitter functions in the brain. It is a key regulator of synaptic plasticity and the modulation of ion channels, as well as the regulation of protein synthesis. Its role in these processes is thought to be crucial for the proper functioning of the brain, and changes in GRIK5 levels or function can have a significant impact on brain function. As a potential drug target or biomarker, GRIK5 is a promising target for the study of a wide range of neurological disorders.

Protein Name: Glutamate Ionotropic Receptor Kainate Type Subunit 5

Functions: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds kainate > quisqualate > domoate > L-glutamate >> AMPA >> NMDA = 1S,3R-ACPD

The "GRIK5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GRIK5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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