GRM1: Key Protein Involved in Sensory Perception and Neurotransmission

Target Name: GRM1

NCBI ID: G2911

GRM1

GRM1: Key Protein Involved in Sensory Perception and Neurotransmission

GRM1 (G protein-coupled receptor 1) is a protein that is expressed in many different tissues in the human body. It is a member of the G protein-coupled receptor family, which is a large family of transmembrane proteins that play an important role in cellular signaling. GRM1 is one of the most widely expressed proteins in the human body, and it is involved in many different processes in the body, including sensory perception, neurotransmission, and hormone regulation.

One of the key functions of GRM1 is its role in sensory perception. The ability to sense the world around us is an essential aspect of our survival, and it is closely tied to the function of GRM1. When we touch, taste, or hear something , our cells send a signal to the brain via GRM1. This signal tells the brain what type of sensory information we are experiencing, and it helps the brain to interpret and respond to that information.

GRM1 is also involved in neurotransmission. When neurons pass information between each other, they release neurotransmitters, which are chemicals that allow communication between neurons. GRM1 is a neurotransmitter receptor that receives neurotransmitters and transmits signals to neurons. These signals can excite or inhibit neurons, thereby affecting communication between neurons.

GRM1 is also closely related to many important biological processes, including cell division, cell cycle, cell signaling, apoptosis, etc. In many diseases, abnormal expression or dysfunction of GRM1 may lead to adverse consequences.

GRM1 is also considered a therapeutic target for many drugs, including antidepressants, antipsychotics, antihypertensive drugs, etc. The mechanism of action of these drugs is usually by binding to GRM1 to affect signaling between neurons, thereby improving patients' symptoms.

In addition, GRM1 is closely related to the occurrence and development of many diseases. For example, abnormal expression or dysfunction of GRM1 is associated with many neurological diseases, such as Alzheimer's disease, Parkinson's disease, epilepsy, etc.

Overall, GRM1 is a very important protein that plays important roles in many different biological processes. With the continuous advancement of technology, our research on GRM1 has become more and more in-depth. Future research will continue to focus on the role of GRM1 in neurological diseases and whether it may become a new drug target.

Protein Name: Glutamate Metabotropic Receptor 1

Functions: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum (PubMed:24603153, PubMed:28886343, PubMed:7476890). May function in the light response in the retina (By similarity)

The "GRM1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GRM1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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