Target Name: GRP
NCBI ID: G2922
Review Report on GRP Target / Biomarker Content of Review Report on GRP Target / Biomarker
GRP
Other Name(s): preproGRP | proGRP | Neuromedin-C | testicular tissue protein Li 103 | gastrin releasing peptide | BN | Gastrin-releasing peptide | Gastrin releasing peptide, transcript variant 1 | GRP18-27 | neuromedin C | pre-progastrin releasing peptide | Neuromedin C | bombesin | GRP-10 | GRP variant 1 | GRP_HUMAN | Pre-progastrin releasing peptide | prepro-GRP | Gastrin-releasing peptide (isoform 1) | Gastrin-releasing peptide preproprotein | Bombesin

GRP-C1: A Potential Drug Target and Biomarker for Cancer

G protein-coupled receptors (GRPs) are a family of transmembrane proteins that play a crucial role in cellular signaling. They are involved in various physiological processes, including sensory perception, neurotransmission, and hormone signaling. GPRs are potential drug targets and have been identified as potential therapeutic targets for various diseases, including cancer, cardiovascular diseases, and neurological disorders. In this article, we will discuss GRP-C1, a drug target and biomarker for various diseases, including cancer.

Background

GRPs are a family of transmembrane proteins that are characterized by the presence of a guanine nucleotide-binding protein (GPPB) and a extracellular domain. They are involved in various physiological processes, including sensory perception, neurotransmission, and hormone signaling. GPRs are potential drug targets and have been identified as potential therapeutic targets for various diseases, including cancer, cardiovascular diseases, and neurological disorders.

GRP-C1: A Potential Drug Target and Biomarker

GRP-C1 is a G protein-coupled receptor that is expressed in various tissues, including the brain, heart, and kidneys. It is involved in the regulation of pain, inflammation, and neurotransmission. GPRs are known to play a crucial role in pain perception and neurotransmission, and GRP-C1 is no exception.

GRP-C1 has been shown to be involved in pain perception and neurotransmission. Studies have shown that GPRs are involved in the regulation of pain perception and neurotransmission, and that they play a crucial role in the development of chronic pain. GRP-C1 has also been shown to be involved in inflammation, as it is involved in the regulation of inflammation in the body.

GRP-C1 has also been shown to be involved in neurotransmission, including the regulation of neurotransmitter release and uptake. Studies have shown that GPRs are involved in the regulation of neurotransmission, and that they play a crucial role in the development of neurotransmitter-related disorders.

GRP-C1 as a Potential Drug Target

GRP-C1 is a potential drug target for various diseases, including cancer. Cancer is a disease that is characterized by the rapid and uncontrolled growth of cells, leading to the development of various tumors. Pain, inflammation, and neurotransmission are involved in the development and progression of cancer, and GPRs are involved in these processes.

GRP-C1 has been shown to be involved in pain perception and neurotransmission, making it a potential drug target for cancer. Studies have shown that GPRs are involved in the regulation of pain perception and neurotransmission in cancer, and that they play a crucial role in the development of pain and neurotransmission in cancer.

GRP-C1 has also been shown to be involved in inflammation in cancer, as it is involved in the regulation of inflammation in the body. Studies have shown that GPRs are involved in the regulation of inflammation in cancer, and that they play a crucial role in the development and progression of inflammation in cancer.

GRP-C1 as a Potential Biomarker

GRP-C1 has also been shown to be a potential biomarker for various diseases, including cancer. Biomarkers are molecules that are derived from within the body and can be used to diagnose, monitor, or predict the progression of a disease. GPRs are involved in various physiological processes, including pain perception, neurotransmission, and inflammation, making them potential biomarkers for a variety of diseases.

GRP-C1 has been shown to be involved in the regulation of pain perception and neurotransmission, making it a potential biomarker for cancer. Studies have shown that GPRs are involved in the regulation of pain perception and neurotransmission in cancer, and that they play a crucial role in the development and progression of cancer-related pain and neurotransmission.

Conclusion

GRP-C1 is a G protein-coupled receptor that is involved in various physiological processes, including pain perception, neurotransmission, and inflammation. It has been shown to be involved in the regulation of pain perception and neurotransmission in cancer, making it a potential drug target and biomarker for cancer. Further research is needed to fully understand the role of GRP-C1 in cancer and its potential as a drug target and biomarker.

Protein Name: Gastrin Releasing Peptide

Functions: Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior (By similarity). Contributes primarily to nonhistaminergic itch sensation (By similarity). In one study, shown to act in the amygdala as part of an inhibitory network which inhibits memory specifically related to learned fear (By similarity). In another study, shown to act on vasoactive intestinal peptide (VIP)-expressing cells in the auditory cortex, most likely via extrasynaptic diffusion from local and long-range sources, to mediate disinhibition of glutamatergic cells via VIP cell-specific GRPR signaling which leads to enhanced auditory fear memories (By similarity). Contributes to the regulation of food intake (By similarity). Inhibits voltage-gated sodium channels but enhances voltage-gated potassium channels in hippocampal neurons (By similarity). Induces sighing by acting directly on the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity (By similarity)

The "GRP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GRP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

GRPEL1 | GRPEL2 | GRPEL2-AS1 | GRPR | GRSF1 | GRTP1 | GRTP1-AS1 | GRWD1 | GRXCR1 | GRXCR2 | GS1-24F4.2 | GS1-600G8.3 | GSAP | GSC | GSC2 | GSDMA | GSDMB | GSDMC | GSDMD | GSDME | GSE1 | GSEC | GSG1 | GSG1L | GSG1L2 | GSK3A | GSK3B | GSKIP | GSN | GSPT1 | GSPT2 | GSR | GSS | GSTA1 | GSTA12P | GSTA2 | GSTA3 | GSTA4 | GSTA5 | GSTA7P | GSTCD | GSTK1 | GSTM1 | GSTM2 | GSTM2P1 | GSTM3 | GSTM4 | GSTM5 | GSTM5P1 | GSTO1 | GSTO2 | GSTP1 | GSTT1 | GSTT2 | GSTT2B | GSTT4 | GSTTP2 | GSTZ1 | GSX1 | GSX2 | GTDC1 | GTF2A1 | GTF2A1L | GTF2A2 | GTF2B | GTF2E1 | GTF2E2 | GTF2F1 | GTF2F2 | GTF2H1 | GTF2H2 | GTF2H2B | GTF2H2C | GTF2H2C_2 | GTF2H3 | GTF2H4 | GTF2H5 | GTF2I | GTF2I-AS1 | GTF2IP1 | GTF2IP12 | GTF2IP20 | GTF2IP4 | GTF2IP7 | GTF2IRD1 | GTF2IRD1P1 | GTF2IRD2 | GTF2IRD2B | GTF2IRD2P1 | GTF3A | GTF3AP5 | GTF3C1 | GTF3C2 | GTF3C2-AS1 | GTF3C3 | GTF3C4 | GTF3C5 | GTF3C6 | GTPase | GTPBP1