ZFATs: Key Proteins in Cellular Processes (G57623)

Target Name: ZFAT

NCBI ID: G57623

ZFAT

ZFATs: Key Proteins in Cellular Processes

ZFAT (Zinc Finger Nucleases) are a family of proteins that play a crucial role in various cellular processes. These proteins are known to interact with a wide range of molecules, including DNA, RNA, and proteins. ZFATs have been implicated in a number of biological processes, including DNA replication, gene expression, and cell signaling.

One of the key features of ZFATs is their ability to recognize specific DNA sequences and to cleave those sequences. This ability is crucial for the regulation of gene expression, as it allows cells to respond to specific cues in the environment. ZFATs have also been shown to play a role in the development and progression of a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The ZFAT gene is located on chromosome 22 and encodes a protein that is composed of 264 amino acids. ZFATs are highly conserved, with only minor differences in their amino acid sequence. They are characterized by a distinct N-terminal region that contains a conserved nucleotide sequence and a C-terminal region that contains a conserved secondary structure.

The ZFAT gene is expressed in many different organisms, including bacteria, archaea, and eukaryotes. ZFATs are also expressed in various cell types, including neurons, macrophages, and dendrites. They are widely expressed in many tissues and have been shown to play a role in a variety of cellular processes, including DNA replication, gene expression, and cell signaling.

One of the most significant functions of ZFATs is their ability to recognize specific DNA sequences and to cleave those sequences. This ability is crucial for the regulation of gene expression, as it allows cells to respond to specific cues in the environment. ZFATs have been shown to interact with a wide range of molecules, including DNA, RNA, and proteins.

ZFATs have been implicated in a number of biological processes, including DNA replication, gene expression, and cell signaling. For example, ZFATs have been shown to play a role in the regulation of DNA replication, as they have been shown to interact with the enzyme responsible for replicating DNA, called DNA polymerase.

ZFATs have also been shown to play a role in the regulation of gene expression. They have been shown to interact with the RNA polymerase, which is responsible for transcribing DNA into RNA. This interaction between ZFATs and RNA polymerase suggests that ZFATs may be involved in the regulation of gene expression.

In addition to their role in gene expression, ZFATs have also been shown to play a role in the regulation of cell signaling. They have been shown to interact with a variety of signaling molecules, including G proteins, which are involved in a variety of cellular signaling pathways. This interaction between ZFATs and G proteins suggests that ZFATs may be involved in the regulation of cell signaling.

The ZFAT gene is located on chromosome 22 and encodes a protein that is composed of 264 amino acids. ZFATs are highly conserved, with only minor differences in their amino acid sequence. They are characterized by a distinct N-terminal region that contains a conserved nucleotide sequence and a C-terminal region that contains a conserved secondary structure.

The study of ZFATs has been an active area of research in recent years, with a number of studies investigating their role in various cellular processes. Further research is needed to fully understand the function of ZFATs and their potential as drug targets or biomarkers.

Protein Name: Zinc Finger And AT-hook Domain Containing

Functions: May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity)

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