Target Name: ZGPAT
NCBI ID: G84619
Review Report on ZGPAT Target / Biomarker Content of Review Report on ZGPAT Target / Biomarker
ZGPAT
Other Name(s): GPATC6 | Zinc finger and G patch domain-containing protein | ZGPAT variant 1 | OTTHUMP00000031596 | ZGPAT variant 4 | Zinc finger CCCH-type and G-patch domain containing, transcript variant 4 | G patch domain-containing protein 6 | Zinc finger CCCH-type with G patch domain-containing protein (isoform c) | g patch domain-containing protein 6 | zinc finger CCCH-type and G-patch domain containing | zinc finger, CCCH-type with G patch domain | ZC3HDC9 | GPATCH6 | ZGPAT_HUMAN | Zinc finger CCCH-type with G patch domain-containing protein | zinc finger CCCH domain-containing protein 9 | ZC3H9 | ZIP | Zinc finger CCCH-type with G patch domain-containing protein (isoform a) | zinc finger and G patch domain-containing protein | MGC44880 | RP4-583P15.3 | Zinc finger CCCH domain-containing protein 9 | OTTHUMP00000031593 | KIAA1847 | Zinc finger CCCH-type and G-patch domain containing, transcript variant 1 | OTTHUMP00000031594

ZGPAT: A Potential Drug Target and Biomarker for Various Diseases

ZGPAT (GPATC6) is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer, neurodegenerative diseases, and psychiatric disorders. ZGPAT is a non-coding RNA molecule that is expressed in a variety of tissues and cells in the body. It is a key regulator of the cell cycle and has been shown to play a role in the development and progression of various diseases.

One of the unique features of ZGPAT is its ability to interact with other molecules in the cell. ZGPAT has been shown to interact with a variety of protein molecules, including the oncogene PDGF-BB and the tumor suppressor protein p53. These interactions have the potential to regulate the activity of these molecules and could be a target for drug development.

In addition to its role in cell signaling, ZGPAT has also been shown to play a role in the regulation of gene expression. ZGPAT has been shown to act as a negative regulator of the gene encoding the protein cyclin D1, which is involved in the G1 phase of the cell cycle. This suggests that ZGPAT may have implications for the treatment of diseases that are characterized by disruptions in the cell cycle, such as cancer.

Another potential drug target for ZGPAT is its role in the development of neurodegenerative diseases. ZGPAT has been shown to be involved in the regulation of the neurotransmitter serotonin, which is involved in a variety of physiological processes in the brain. ZGPAT has also been shown to interact with the protein TrkB, which is involved in the regulation of serotonin receptors. These interactions suggest that ZGPAT may be a potential target for the treatment of neurodegenerative diseases.

In addition to its potential drug targets, ZGPAT has also been shown to have potential as a biomarker for a variety of diseases. For example, ZGPAT has been shown to be elevated in the brains of individuals with Alzheimer's disease, a neurodegenerative disease. Additionally, ZGPAT has been shown to be decreased in the brains of individuals with Parkinson's disease, another neurodegenerative disease. These findings suggest that ZGPAT may be a potential biomarker for the diagnosis and treatment of neurodegenerative diseases.

Overall, ZGPAT is a gene that has the potential to be a drug target or biomarker for a variety of diseases. Its unique ability to interact with other molecules in the cell and its role in the regulation of gene expression make it an attractive target for drug development. Additionally, its potential as a biomarker for neurodegenerative diseases adds to its potential utility as a therapeutic tool. Further research is needed to fully understand the role of ZGPAT in disease and to develop effective treatments.

Protein Name: Zinc Finger CCCH-type And G-patch Domain Containing

Functions: Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis

The "ZGPAT Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZGPAT comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ZGRF1 | ZHX1 | ZHX1-C8orf76 | ZHX2 | ZHX3 | ZIC1 | ZIC2 | ZIC3 | ZIC4 | ZIC5 | ZIK1 | ZIM2 | ZIM3 | Zinc finger protein GLI | ZKSCAN1 | ZKSCAN2 | ZKSCAN3 | ZKSCAN4 | ZKSCAN5 | ZKSCAN7 | ZKSCAN8 | ZKSCAN8P1 | ZMAT1 | ZMAT2 | ZMAT3 | ZMAT4 | ZMAT5 | ZMIZ1 | ZMIZ1-AS1 | ZMIZ2 | ZMPSTE24 | ZMYM1 | ZMYM2 | ZMYM3 | ZMYM4 | ZMYM4-AS1 | ZMYM5 | ZMYM6 | ZMYND10 | ZMYND11 | ZMYND12 | ZMYND15 | ZMYND19 | ZMYND8 | ZNF10 | ZNF100 | ZNF101 | ZNF106 | ZNF107 | ZNF112 | ZNF114 | ZNF117 | ZNF12 | ZNF121 | ZNF124 | ZNF131 | ZNF132 | ZNF133 | ZNF134 | ZNF135 | ZNF136 | ZNF137P | ZNF138 | ZNF14 | ZNF140 | ZNF141 | ZNF142 | ZNF143 | ZNF146 | ZNF148 | ZNF154 | ZNF155 | ZNF157 | ZNF16 | ZNF160 | ZNF165 | ZNF169 | ZNF17 | ZNF174 | ZNF175 | ZNF177 | ZNF18 | ZNF180 | ZNF181 | ZNF182 | ZNF184 | ZNF185 | ZNF189 | ZNF19 | ZNF195 | ZNF197 | ZNF2 | ZNF20 | ZNF200 | ZNF202 | ZNF204P | ZNF205 | ZNF205-AS1 | ZNF207 | ZNF208