Target Name: ZFP92
NCBI ID: G139735
Review Report on ZFP92 Target / Biomarker Content of Review Report on ZFP92 Target / Biomarker
ZFP92
Other Name(s): ZFP92_HUMAN | Zinc finger protein 92 homolog (isoform 1) | ZFP92 variant 1 | ZFP92 zinc finger protein | ZNF897 | zinc finger protein homologous to Zfp92 in mouse | Zfp-92 | Zinc finger protein 92 homolog | Zinc finger protein homologous to Zfp92 in mouse | ZFP92 zinc finger protein, transcript variant 1

ZFP92: A Potential Drug Target and Biomarker

ZFP92 is a gene that encodes for a protein known as ZFP92, which is a key regulator of microRNA (miRNA) levels in the human body. ZFP92 plays a crucial role in the regulation of various cellular processes, including cell growth, differentiation, and programmed cell death. ZFP92 has also been implicated in several diseases, including cancer, neurodegenerative diseases, and developmental disorders. As a result, ZFP92 has emerged as a promising drug target and biomarker for a variety of diseases.

The ZFP92 Protein and Its Functions

ZFP92 is a 21-kDa protein that is expressed in various tissues and cells in the human body. It is composed of 192 amino acid residues and has a calculated pI of 5.97. ZFP92 is primarily localized to the cytoplasm and is associated with the endoplasmic reticulum (ER) and the transmembrane protein (TBP).

The ZFP92 protein has several key functions that are crucial for its normal function in the body. One of its most important functions is the regulation of miRNA levels. ZFP92 has been shown to interact with miRNA-21, a well-known regulator of cancer risk, and to play a role in the negative regulation of miRNA-21 levels. This interaction between ZFP92 and miRNA-21 suggests that ZFP92 may be a potential drug target for cancer.

Another function of ZFP92 is the regulation of cellular processes such as cell growth, apoptosis (programmed cell death), and angiogenesis (the formation of new blood vessels). ZFP92 has been shown to play a role in the regulation of cell growth by controlling the activity of the oncogene transforming growth factor-尾1 (TGF-β1). This function may make ZFP92 a potential drug target for neurodegenerative diseases.

In addition to its functions in cellular processes, ZFP92 has also been implicated in the regulation of gene expression and protein synthesis. ZFP92 has been shown to interact with several transcription factors, including NF-kappa-B, AP-1, and STAT3. This interaction between ZFP92 and these transcription factors suggests that ZFP92 may be a potential drug target for diseases that are characterized by inflammation, oxidative stress, or other disruptions in gene expression.

The ZFP92-Driven Pathway

The ZFP92-driven pathway is a complex regulatory network that is involved in the regulation of various cellular processes in the body. The ZFP92 protein has been shown to play a key role in this network by controlling the activity ofmiRNA-21, a key regulator of cancer risk.

The ZFP92-miRNA-21 complex has been shown to have a negative impact on the levels of miRNA-21 in the body, which may lead to the activation of miRNA-21's negative regulators. This activation of miRNA-21's negative regulators may contribute to the inhibition of miRNA-21's positive regulators, including ZFP92.

The ZFP92-miRNA-21 complex is also involved in the regulation of cellular processes such as cell growth, apoptosis, and angiogenesis. ZFP92 has been shown to play a role in the regulation of cell growth by controlling the activity of TGF-β1, a key regulator of cell growth and differentiation. This function

Protein Name: ZFP92 Zinc Finger Protein

Functions: May be involved in transcriptional regulation

The "ZFP92 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZFP92 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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