Target Name: ZHX2
NCBI ID: G22882
Review Report on ZHX2 Target / Biomarker Content of Review Report on ZHX2 Target / Biomarker
ZHX2
Other Name(s): regulator of AFP | alpha-fetoprotein regulator 1 | Zinc fingers and homeoboxes 2, transcript variant 2 | zinc fingers and homeoboxes 2 | KIAA0854 | Transcription factor ZHX2 | Alpha-fetoprotein regulator 1 | AFP regulator 1 | RAF | Zinc fingers and homeoboxes protein 2 | AFR1 | Zinc finger and homeodomain protein 2 | ZHX2_HUMAN | Zinc-fingers and homeoboxes 2 | transcription factor ZHX2 | Regulator of AFP | ZHX2 variant 2 | zinc finger and homeodomain protein 2

ZHX2: A Promising Regulator of Angiotensin II (AFP) and a Potential Drug Target

Introduction

Angiotensin II (AFP) is a potent mediator of various physiological processes in the body, including blood pressure, blood volume, and blood cell production. It is a pro-inflammatory molecule that plays a crucial role in maintaining cardiovascular health. However, uncontrolled levels of AFI can also contribute to the development and progression of various diseases, such as heart failure, hypertension, and cancer. The regulation of AFI by various biomolecules, including ZHX2, is critical for maintaining physiological balance and preventing disease.

ZHX2: ARegulator ofAFP andAPC

ZHX2 is a non-coding RNA molecule that was identified as a potential regulator of AFI. It is expressed in various tissues and cell types and has been shown to interact with AFI. Several studies have demonstrated that ZHX2 can modulate the activity of AFI, including its ability to stimulate inflammation and promote cell proliferation.

ZHX2 is a key regulator of AFI-induced inflammation

AFI is a potent mediator of inflammation and has been shown to contribute to the development of various inflammatory diseases, including cancer. ZHX2 has been shown to regulate the activity of AFI in a variety of cell types, including immune cells and cancer cells.

ZHX2 is a negative regulator of AFI-induced cell proliferation

AFI is also a potent regulator of cell proliferation and has been shown to contribute to the development of various cancer types. ZHX2 has been shown to inhibit the activity of AFI and prevent it from promoting cell proliferation.

ZHX2 is a potential drug target for various diseases

The regulation of AFI by ZHX2 is a promising direction for the development of new drugs for various diseases, including cancer, cardiovascular disease, and neurodegenerative diseases. ZHX2 has been shown to be involved in several signaling pathways that are involved in these diseases, including the regulation of cell cycle, apoptosis, and inflammation.

Conclusion

In conclusion, ZHX2 is a promising regulator of AFI and has the potential to be a drug target for various diseases. Further studies are needed to fully understand the regulation of AFI by ZHX2 and its potential therapeutic applications.

Protein Name: Zinc Fingers And Homeoboxes 2

Functions: Acts as a transcriptional repressor (PubMed:12741956). Represses the promoter activity of the CDC25C gene stimulated by NFYA (PubMed:12741956). May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells (By similarity). In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex (By similarity)

The "ZHX2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZHX2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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