ZFYVE27: A Drug Target / Disease Biomarker (G118813)
ZFYVE27: A Drug Target / Disease Biomarker
ZFYVE27 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the Z-type actinin family, which is characterized by the presence of a Z-shaped arrangement of multiple domains in the protein sequence. ZFYVE27 is of particular interest as a potential drug target due to its unique structure and the involvement of multiple signaling pathways in its regulation.
The Z-type actinin family is a subfamily of actinin proteins that are characterized by the presence of a Z-shaped arrangement of multiple domains in their sequence. This arrangement is thought to give these proteins their unique structure and function, as it allows them to interact with a variety of different signaling pathways. ZFYVE27 is no exception to this rule, as it is characterized by a Z-shaped arrangement of multiple domains that give it its unique structure and function.
One of the key features of ZFYVE27 is its ability to interact with multiple signaling pathways. This is due to the presence of multiple domains in its sequence, which allow it to interact with a variety of different signaling pathways. For example, ZFYVE27 has been shown to interact with the protein kinase A尾4, which is involved in the regulation of a variety of cellular processes, including cell signaling and inflammation. This interaction between ZFYVE27 and A尾4 suggests that it may be a useful drug target for the treatment of a variety of diseases.
Another potential mechanism by which ZFYVE27 may be involved in disease is its role in the regulation of inflammation. Inflammation is a complex biological process that is involved in the host's response to injury or infection. ZFYVE27 has been shown to be involved in the regulation of inflammation, as it has been shown to play a role in the recruitment of immune cells to the site of inflammation. This suggests that ZFYVE27 may be a useful drug target for the treatment of inflammatory diseases.
In addition to its potential role in inflammation, ZFYVE27 is also of interest as a potential drug target due to its involvement in the regulation of cell signaling. Cell signaling is a critical process that is involved in the regulation of a wide variety of cellular processes, including cell growth, differentiation, and survival. ZFYVE27 has been shown to be involved in the regulation of cell signaling, as it has been shown to play a role in the regulation of the protein kinase PDGFR-尾. This suggests that ZFYVE27 may be a useful drug target for the treatment of a variety of diseases that are characterized by the regulation of cell signaling.
Overall, ZFYVE27 is a protein that is of particular interest as a potential drug target due to its unique structure and the involvement of multiple signaling pathways in its regulation. Its ability to interact with multiple signaling pathways, including the regulation of inflammation and cell signaling, suggests that it may be a useful target for the treatment of a variety of diseases. Further research is needed to fully understand the role of ZFYVE27 in disease and to develop effective treatments based on its unique properties.
Protein Name: Zinc Finger FYVE-type Containing 27
Functions: Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport (PubMed:17082457). Promotes axonal elongation and contributes to the establishment of neuronal cell polarity (By similarity). Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner (PubMed:19289470). Contributes to both the formation and stabilization of the tubular ER network (PubMed:24668814). Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections (PubMed:23969831). Acts as an adapter protein and facilitates the interaction of KIF5A with VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 and the ZFYVE27-KIF5A complex contributes to the transport of these proteins in neurons. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a KIF5A/B-dependent manner (PubMed:21976701)
The "ZFYVE27 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZFYVE27 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
ZFYVE28 | ZFYVE9 | ZFYVE9P1 | ZG16 | ZG16B | ZGLP1 | ZGPAT | ZGRF1 | ZHX1 | ZHX1-C8orf76 | ZHX2 | ZHX3 | ZIC1 | ZIC2 | ZIC3 | ZIC4 | ZIC5 | ZIK1 | ZIM2 | ZIM3 | Zinc finger protein GLI | ZKSCAN1 | ZKSCAN2 | ZKSCAN3 | ZKSCAN4 | ZKSCAN5 | ZKSCAN7 | ZKSCAN8 | ZKSCAN8P1 | ZMAT1 | ZMAT2 | ZMAT3 | ZMAT4 | ZMAT5 | ZMIZ1 | ZMIZ1-AS1 | ZMIZ2 | ZMPSTE24 | ZMYM1 | ZMYM2 | ZMYM3 | ZMYM4 | ZMYM4-AS1 | ZMYM5 | ZMYM6 | ZMYND10 | ZMYND11 | ZMYND12 | ZMYND15 | ZMYND19 | ZMYND8 | ZNF10 | ZNF100 | ZNF101 | ZNF106 | ZNF107 | ZNF112 | ZNF114 | ZNF117 | ZNF12 | ZNF121 | ZNF124 | ZNF131 | ZNF132 | ZNF133 | ZNF134 | ZNF135 | ZNF136 | ZNF137P | ZNF138 | ZNF14 | ZNF140 | ZNF141 | ZNF142 | ZNF143 | ZNF146 | ZNF148 | ZNF154 | ZNF155 | ZNF157 | ZNF16 | ZNF160 | ZNF165 | ZNF169 | ZNF17 | ZNF174 | ZNF175 | ZNF177 | ZNF18 | ZNF180 | ZNF181 | ZNF182 | ZNF184 | ZNF185 | ZNF189 | ZNF19 | ZNF195 | ZNF197 | ZNF2 | ZNF20
