ZG16: A Key Member of The ZFG-CGR Family (G653808)
ZG16: A Key Member of The ZFG-CGR Family
ZG16 (ZG16A) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the Zinc Finger G protein-coupled receptor (ZFG-CGR) family, which is a subfamily of the Zinc Finger Transmembrane Protein (ZF-TMP) superfamily. ZG16 is also known as ZG16A, ZG16B, or ZG16-containing protein (ZCPP).
The ZFG-CGR family is characterized by the presence of a Zn2+-dependent intracellular signaling pathway. This pathway involves the recruitment of Zn2+ ions to the protein, which then triggers a series of downstream signaling cascades that can modulate various cellular processes, including cell proliferation, differentiation, migration, and survival. ZG16 is a key component of this signaling pathway, as it plays a critical role in the regulation of neuronal excitability and synaptic plasticity.
ZG16 is a transmembrane protein that is expressed in a variety of tissues, including the brain, heart, and kidneys. It is primarily localized to the brain, where it is involved in the regulation of neuronal excitability and synaptic plasticity. ZG16 is a potent modulator of the electrical activity of neurons, and its expression has been linked to the development and progression of a number of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and epilepsy.
One of the key functions of ZG16 is its role in modulating the strength and pattern of neural synaptic plasticity. Synaptic plasticity is the ability of neurons to change in response to experience, and it is a critical factor in the development and maintenance of neural circuits. ZG16 has been shown to play a critical role in the regulation of synaptic plasticity, as it is involved in the intracellular signaling cascade that promotes the strengthening of synaptic connections.
In addition to its role in synaptic plasticity, ZG16 is also involved in the regulation of neuronal excitability. Neuronal excitability refers to the ability of neurons to generate electrical impulses, and it is a critical factor in the transmission of information in the nervous system. ZG16 is involved in the regulation of neuronal excitability through its role in the intracellular signaling pathway that promotes the strengthening of synaptic connections. This regulation is important for the proper functioning of neural circuits, and is implicated in a number of neurological and psychiatric disorders.
The ZFG-CGR family is a subset of the Zinc Finger Transmembrane Protein (ZF-TMP) superfamily, which is characterized by the presence of a Zn2+-dependent transmembrane domain and a cytoplasmic tail. ZF-TMP proteins are involved in a wide range of cellular processes, including cell signaling, cytoskeletal organization, and intracellular signaling. ZG16 is a member of the ZFG-CGR family, and its function is similar to that of other ZF-TMP proteins.
The ZFG-CGR family is a relatively small gene family that is expressed in a variety of tissues, including the brain, heart, and kidneys. ZG16 is one of the most well-studied ZF-TMP proteins, and its function is likely to be similar to that of other members of the ZFG-CGR family. ZG16 is a transmembrane protein that is involved in the regulation of intracellular signaling pathways, including the modulation of neuronal excitability and synaptic plasticity. Further research is needed to fully understand the
Protein Name: Zymogen Granule Protein 16
Functions: May play a role in protein trafficking. May act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN
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More Common Targets
ZG16B | ZGLP1 | ZGPAT | ZGRF1 | ZHX1 | ZHX1-C8orf76 | ZHX2 | ZHX3 | ZIC1 | ZIC2 | ZIC3 | ZIC4 | ZIC5 | ZIK1 | ZIM2 | ZIM3 | Zinc finger protein GLI | ZKSCAN1 | ZKSCAN2 | ZKSCAN3 | ZKSCAN4 | ZKSCAN5 | ZKSCAN7 | ZKSCAN8 | ZKSCAN8P1 | ZMAT1 | ZMAT2 | ZMAT3 | ZMAT4 | ZMAT5 | ZMIZ1 | ZMIZ1-AS1 | ZMIZ2 | ZMPSTE24 | ZMYM1 | ZMYM2 | ZMYM3 | ZMYM4 | ZMYM4-AS1 | ZMYM5 | ZMYM6 | ZMYND10 | ZMYND11 | ZMYND12 | ZMYND15 | ZMYND19 | ZMYND8 | ZNF10 | ZNF100 | ZNF101 | ZNF106 | ZNF107 | ZNF112 | ZNF114 | ZNF117 | ZNF12 | ZNF121 | ZNF124 | ZNF131 | ZNF132 | ZNF133 | ZNF134 | ZNF135 | ZNF136 | ZNF137P | ZNF138 | ZNF14 | ZNF140 | ZNF141 | ZNF142 | ZNF143 | ZNF146 | ZNF148 | ZNF154 | ZNF155 | ZNF157 | ZNF16 | ZNF160 | ZNF165 | ZNF169 | ZNF17 | ZNF174 | ZNF175 | ZNF177 | ZNF18 | ZNF180 | ZNF181 | ZNF182 | ZNF184 | ZNF185 | ZNF189 | ZNF19 | ZNF195 | ZNF197 | ZNF2 | ZNF20 | ZNF200 | ZNF202 | ZNF204P | ZNF205
