Target Name: ZG16B
NCBI ID: G124220
Review Report on ZG16B Target / Biomarker Content of Review Report on ZG16B Target / Biomarker
ZG16B
Other Name(s): PRO1567 | jacalin-like lectin domain containing 2 | ZG16B_HUMAN | Zymogen granule protein 16 homolog B precursor | Endocrine and exocrine protein | PAUF | HRPE773 | JCLN2 | Jacalin-like lectin domain containing 2 | pancreatic adenocarcinoma upregulated factor | Pancreatic adenocarcinoma upregulated factor | Zymogen granule protein 16 homolog B | EECP | Zymogen granule protein 16B | endocrine and exocrine protein | zymogen granule protein 16B

ZG16B: A Proteins of Diverse Functions and Potential Drug Targets

ZG16B (PRO1567) is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and muscle. It is a member of the G-protein-coupled receptor (GPCR) family, which is a large superfamily of transmembrane proteins that play a critical role in cellular signaling. ZG16B is characterized by a long N-terminus that is rich in conserved charge and a convoluted structure containing multiple leucines.

The ZG16B protein is involved in a wide range of physiological processes in the body, including neurotransmitter signaling, hormone signaling, and cellular signaling. It is a key regulator of several signaling pathways, including neuro-endocrine signaling pathways, cell proliferation and differentiation signaling pathways and apoptosis signaling pathways, etc. In the neuro-endocrine signaling pathway, ZG16B regulates the development and function of the nervous system by binding to hormone molecules, such as thyroxine and norepinephrine.

ZG16B is also involved in the regulation of cellular signaling in various tissues. In the liver, ZG16B is a critical regulator of the bile salt receptor, which is responsible for the production and secretion of bile salts. In the heart, ZG16B is involved in the regulation of contractility and cardiac rhythm. In the muscle, ZG16B is involved in the regulation of muscle growth and myogenesis.

In addition, ZG16B is also a potential drug target in several diseases. For example, ZG16B has been shown to be involved in the development and progression of several types of cancer, including neurobladder cancer, breast cancer, and colorectal cancer. has also been shown to be involved in the regulation of several diseases, including diabetes, obesity, and neurodegenerative diseases.

In conclusion, ZG16B is a well-characterized protein that is involved in a wide range of physiological processes in the body. Its function as a regulator of GPCR signaling pathways makes it a potential drug target in several diseases. Further research is needed to fully understand the role of ZG16B in cellular signaling and its potential as a drug target.

Protein Name: Zymogen Granule Protein 16B

The "ZG16B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZG16B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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