Target Name: HES4
NCBI ID: G57801
Review Report on HES4 Target / Biomarker Content of Review Report on HES4 Target / Biomarker
HES4
Other Name(s): bHLHb42 | hHES4 | Class B basic helix-loop-helix protein 42 | OTTHUMP00000038449 | Hairy and enhancer of split 4 | Hes family bHLH transcription factor 4, transcript variant 2 | HES4 variant 1 | Transcription factor HES-4 (isoform 2) | bHLH factor Hes4 | Transcription factor HES-4 | Transcription factor HES-4 (isoform 1) | Hes family bHLH transcription factor 4, transcript variant 1 | hairy and enhancer of split 4 | class B basic helix-loop-helix protein 42 | HES4_HUMAN | hes family bHLH transcription factor 4 | HES4 variant 2

HES4: A Non-Coding RNA Molecule with Potential as A Drug Target and Biomarker

HES4 (bHLHb42) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. Its unique structure and biology make it an attractive target for researchers to study and develop new treatments.

HES4 is a small RNA molecule that is expressed in various tissues and cells throughout the body. It is a member of the homeobox gene family, which is known for the production of proteins involved in development and tissue repair. The bHLHb42 gene is a non- coding RNA molecule that is located on chromosome 16p13.3.

One of the unique features of HES4 is its ability to self-assemble into a stable and functional RNA molecule. This self-assembly process, known as \"self-healing,\" allows the molecule to survive in a variety of cellular environments and to remain stable even in the presence of cellular stressors.

HES4 has been shown to play a role in various cellular processes, including cell growth, differentiation, and the regulation of gene expression. It has also been linked to the development and progression of various diseases, including cancer.

One of the most promising aspects of HES4 is its potential as a drug target. By targeting the bHLHb42 gene, researchers can potentially disrupt its function and reduce the risk of disease. This is an attractive idea because many diseases are caused by the over-production or dysfunction of specific genes. By blocking the function of HES4, researchers can potentially develop new treatments for a variety of diseases.

Another potential application of HES4 is as a biomarker. The molecule has been shown to be expressed in various tissues and cells, including cancer cells, and can be used as a protein biomarker for cancer diagnosis and treatment. This makes it an attractive option for researchers to develop new diagnostic tests for cancer and to identify new targets for cancer treatments.

In addition to its potential as a drug target and biomarker, HES4 is also of interest to researchers because of its unique biology. The self-assembly process of HES4 is still not well understood, and researchers are still trying to determine the full implications of this process. This lack of understanding may make it difficult to develop effective treatments for HES4-related diseases.

Overall, HES4 is a promising molecule for drug targeting and biomarker research. Its unique structure and biology make it an attractive target for researchers to study and develop new treatments for a variety of diseases. Further research is needed to fully understand the potential of this molecule and to develop effective treatments.

Protein Name: Hes Family BHLH Transcription Factor 4

Functions: Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3' (By similarity)

The "HES4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HES4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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