ISY1-RAB43: A Drug Target / Disease Biomarker (G100534599)

Target Name: ISY1-RAB43

NCBI ID: G100534599

ISY1-RAB43

ISY1-RAB43: A Drug Target / Disease Biomarker

ISY1-RAB43 is a protein that is expressed in various tissues throughout the body, including the brain, pancreas, and gastrointestinal tract. It is a member of the ISY family of proteins, which are known for their role in cell signaling and development. ISY1-RAB43 has been shown to play a role in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, it has become a focus of interest for researchers studying these conditions and for developing new treatments.

One of the unique features of ISY1-RAB43 is its structure. It is a transmembrane protein that spans the cell membrane and is involved in various signaling pathways. It consists of a cytoplasmic tail that is involved in cell adhesion and a transmembrane region that contains several unique domains, including a N-terminal transmembrane domain, a transmembrane domain, and a C-terminal cytoplasmic domain. The transmembrane domain is thought to play a key role in the protein's ability to interact with other molecules on the cell surface and in its signaling functions.

ISY1-RAB43 is involved in several signaling pathways that are important for both normal development and disease. One of the most well-studied functions of ISY1-RAB43 is its role in the development and progression of cancer. Many studies have shown that ISY1-RAB43 is highly expressed in various types of cancer, including breast, ovarian, and colorectal cancer. It is also often overexpressed in these cancers, which may contribute to their progression and the development of invasive and metastatic forms.

Another area of interest for ISY1-RAB43 is its role in neurodegenerative diseases. Many of these conditions, including Alzheimer's disease, Parkinson's disease, and Huntington's disease, are characterized by the progressive loss of brain cells and the development of neurofibrillary tangles. ISY1-RAB43 has been shown to be involved in the development and progression of these conditions, and may be a potential drug target or biomarker for these diseases.

In addition to its involvement in cancer and neurodegenerative diseases, ISY1-RAB43 is also thought to be involved in autoimmune disorders. Many of these conditions, including rheumatoid arthritis, lupus, and multiple sclerosis, are characterized by the immune system attacking the body's own tissues and organs. ISY1-RAB43 has been shown to be involved in the development and progression of these conditions, and may be a potential drug target or biomarker for these diseases as well.

Despite the potential for ISY1-RAB43 as a drug target or biomarker, much more research is needed to fully understand its role in these diseases. Many studies are needed to determine the exact mechanism of ISY1-RAB43's involvement in cancer, neurodegenerative diseases, and autoimmune disorders. In addition, there is a need for better understanding of the protein's structure and function, as well as its potential clinical applications.

In conclusion, ISY1-RAB43 is a protein that is expressed in various tissues throughout the body and is involved in several signaling pathways that are important for both normal development and disease. Its involvement in cancer, neurodegenerative diseases, and autoimmune disorders has made it a focus of interest for researchers studying these conditions and for developing new treatments. Further research is needed to fully understand the protein's role in these diseases and its potential clinical applications.

Protein Name: ISY1-RAB43 Readthrough

Functions: Component of the spliceosome C complex required for the selective processing of microRNAs during embryonic stem cell differentiation (By similarity). Required for the biogenesis of all miRNAs from the pri-miR-17-92 primary transcript except miR-92a (By similarity). Only required for the biogenesis of miR-290 and miR-96 from the pri-miR-290-295 and pri-miR-96-183 primary transcripts, respectively (By similarity). Required during the transition of embryonic stem cells (ESCs) from the naive to primed state (By similarity). By enhancing miRNA biogenesis, promotes exit of ESCs from the naive state to an intermediate state of poised pluripotency, which precedes transition to the primed state (By similarity). Involved in pre-mRNA splicing as component of the spliceosome

The "ISY1-RAB43 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ISY1-RAB43 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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