ITPR1-DT: A Promising Drug Target / Biomarker (G100996539)

Target Name: ITPR1-DT

NCBI ID: G100996539

ITPR1-DT

Other Name(s): ITPR1-AS1 | ITPR1 divergent transcript

ITPR1-DT: A Promising Drug Target / Biomarker

ITPR1-DT is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and kidneys. Its full name is ITPR1-alpha-globulin, which is a type of transmembrane protein that is characterized by the presence of a long N-terminus and a unique topology of its transmembrane region.

ITPR1-DT has been identified as a potential drug target in the field of neurodegenerative diseases, due to its involvement in the regulation of cellular processes that are important for the maintenance of neuronal structure and function. The protein has also been shown to play a role in the regulation of inflammation, which is a key factor in the development of a number of neurodegenerative diseases.

Targeting ITPR1-DT

One of the main goals of drug development is to identify small molecules that can selectively target a protein of interest and modulate its activity. This can lead to the development of new treatments for a wide range of diseases.

In the case of ITPR1-DT, researchers have identified a number of potential small molecules that can selectively target the protein and modulate its activity. These molecules include inhibitors of tyrosination, which is the process by which the protein is modified with tyrosine, a chemical that can modulate its structure and function.

An inhibitor of tyrosination has been shown to be particularly effective in modulating the activity of ITPR1-DT. This compound, called ITP-150, was shown to inhibit tyrosination of ITPR1-DT and to protect against the neurotoxicity associated with its overexpression.

Another potential small molecule that can target ITPR1-DT is a peptide derived from the N-terminus of the protein. This peptide, called NP-1, was shown to be able to inhibit the tyrosination of ITPR1-DT and to protect against its neurotoxicity.

In addition to inhibitors of tyrosination, researchers have also identified a number of other potential small molecules that can target ITPR1-DT. These include small molecules that can modulate the structure and function of the protein itself, as well as molecules that can affect the activity of ITPR1-DT in other cellular processes.

Conclusion

In conclusion, ITPR1-DT is a protein that is involved in a number of important cellular processes, including the regulation of cellular growth, differentiation, and inflammation. Its potential as a drug target makes it an attractive target for the development of new treatments for a wide range of neurodegenerative diseases. The inhibition of tyrosination, as well as the use of small molecules that can modulate the structure and function of ITPR1-DT, hold great promise for the development of new treatments for these diseases. Further research is needed to fully understand the role of ITPR1-DT as a drug target and to develop effective treatments for the associated neurological disorders.

Protein Name: ITPR1 Divergent Transcript

The "ITPR1-DT Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ITPR1-DT comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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