Myosin (IVL) Troponin: Regulation of Muscle Contraction, Relaxation, Cell Proliferation and Apoptosis

Target Name: IVL

NCBI ID: G3713

Content of Review Report on IVL Target / Biomarker

IVL

Other Name(s): involucrin | INVO_HUMAN | Involucrin

Myosin (IVL) Troponin: Regulation of Muscle Contraction, Relaxation, Cell Proliferation and Apoptosis

Intracellular signaling pathways play a crucial role in the regulation of various cellular processes in the body. One of the key signaling pathways is the intracellular signaling pathway, also known as the PI3K/Akt signaling pathway. This pathway is involved in the regulation of cell proliferation , survival, and angiogenesis. One of the key proteins involved in this pathway is the myosin (IVL) troponin.

Myosin (IVL) Troponin is a protein with a molecular weight of 44KD, which is synthesized and secreted by the sarcolemma in muscle cells. The sarcoplasmic reticulum is a complex membrane system within cells, responsible for the synthesis and modification of various cell membrane proteins. Myosin (IVL) Troponin plays a key role in the process of muscle contraction and relaxation and is an important player in the process of muscle contraction and relaxation.

Structure and function of myosin (IVL) troponin

Myosin (IVL) Troponin is composed of two subunits, N-myosin (N-IVL) and C-myosin (C-IVL). The two subunits are held together by non-covalent interactions to form a dimer. Myosin (IVL) The dimeric structure of troponin allows it to play an important role in intracellular transport and degradation.

Myosin (IVL) The functions of troponin are mainly reflected in the following aspects:

1. Muscle contraction

Myosin (IVL) Troponin plays a key role in muscle contraction. Muscle cells require a large amount of myosin (IVL) troponin to participate in the contraction process. These myosin (IVL) troponin combine with myosin (glutamic acid phosphatase, GAP) to form GAP-IVL-myosin. protein (GAP-IVL-troponin) complex, thereby promoting the increase in Ca2+ concentration in muscle cells, causing muscle cells to produce contractile force.

2. Muscle relaxation

Myosin (IVL) Troponin also plays a key role in the muscle relaxation process. During the relaxation process of muscle cells, a large amount of myosin (IVL) troponin is required to participate. These myosin (IVL) troponin combine with myosin (glutamic acid phosphatase, GAP) to form GAP-IVL-myosin. protein (GAP-IVL-troponin) complex, thereby inhibiting the increase in Ca2+ concentration in muscle cells and causing muscle cell relaxation.

3. Cell proliferation and survival

Myosin (IVL) troponin also plays a key role in cell proliferation and survival. Myosin (IVL) troponin can combine with myosin (glutamic acid phosphatase, GAP) to form a GAP-IVL-myosin (GAP-IVL-troponin) complex, thereby promoting Ca2+ in muscle cells Increased concentrations increase muscle cell proliferation and survival.

4. Apoptosis

Myosin (IVL) troponin also plays a key role in the apoptosis process. Myosin (IVL) troponin can combine with myosin (glutamic acid phosphatase, GAP) to form a GAP-IVL-myosin (GAP-IVL-troponin) complex, thereby promoting Ca2+ in muscle cells Increased concentration increases the possibility of muscle cell apoptosis.

Myosin (IVL) troponin plays a key role in muscle contraction, relaxation, cell proliferation and survival, and apoptosis. These effects make myosin (IVL) troponin a very valuable drug

Protein Name: Involucrin

Functions: Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia

The "IVL Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IVL comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
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