JADE3: A Potential Drug Target and Biomarker (G9767)

Target Name: JADE3

NCBI ID: G9767

JADE3

JADE3: A Potential Drug Target and Biomarker

JADE3 (Jade Family PHD Finger Protein 3) is a protein that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function have made it an attractive target for researchers to study, and its potential as a drug or biomarker has led to a growing interest in the field of bioinformatics and medical science.

Structure and Function

JADE3 is a member of the Jade Family of proteins, which are characterized by their unique monoclonal structure and diverse functions. The Jade Family is a growing area of research, with many studies showing the involvement of these proteins in various physiological processes. JADE3 is a 14kDa protein that is expressed in various tissues and cells in the body, including the brain, heart, and liver.

One of the key features of JADE3 is its PHD (poly(diphtyldisulfide)) domain. This domain is composed of a series of alternating beta-strands and alpha-helices, and is responsible for JADE3's unique structure and stability. The PHD domain is involved in JADE3's stability and functions as a scaffold, interacting with various protein partners to regulate its activity.

JADE3's PHD domain is also involved in its unique structure and function. The beta-strands in the PHD domain form a strong interaction with the surrounding protein, while the alpha-helices provide a flexible framework that allows for various conformational changes. This interaction between the beta-strands and alpha-helices allows JADE3 to exist in a variety of conformational states, which are important for its function.

In addition to its unique structure, JADE3's PHD domain is also involved in its biology. Many studies have shown that the PHD domain plays a role in the regulation of various cellular processes, including cell adhesion, migration, and invasion. In addition, the PHD domain has also been shown to be involved in the regulation of inflammation, as well as in the development and progression of various diseases.

Potential Applications

JADE3's unique structure and function make it an attractive target for drug research and development. Its PHD domain has been shown to be involved in various cellular processes, making it a potential target for small molecules that can modulate its activity. Additionally, JADE3's monoclonal structure and variety of functions make it a potential biomarker for various diseases.

In the context of cancer, JADE3's PHD domain has been shown to be involved in the regulation of cell adhesion and migration, as well as in the development and progression of various types of cancer. Therefore, JADE3 may be a potential target for cancer therapies that target these processes. Additionally, JADE3's PHD domain has also been shown to be involved in the regulation of inflammation, which may make it a potential target for therapies that target inflammation.

In the context of neurodegenerative diseases, JADE3's PHD domain has been shown to be involved in the regulation of protein synthesis and cellular processes that are important for the maintenance of neural tissue health. Therefore, JADE3 may be a potential target for therapies that target these processes.

In addition to its potential as a drug target or biomarker, JADE3's unique structure and function also make it an attractive target for biotechnology and bioremediation. Its PHD domain can be used to develop new diagnostic tools or therapeutic agents, as well as for the production of various biosensors.

Conclusion

JADE3 is a unique protein with a variety of structures and functions that make it an attractive target for

Protein Name: Jade Family PHD Finger 3

Functions: Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity

The "JADE3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about JADE3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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