Target Name: JAG2
NCBI ID: G3714
Review Report on JAG2 Target / Biomarker Content of Review Report on JAG2 Target / Biomarker
JAG2
Other Name(s): LGMDR27 | Jagged2 | JAG2 variant 1 | Jagged canonical Notch ligand 2, transcript variant 1 | jagged canonical Notch ligand 2 | Protein jagged-2 (isoform a) | hJ2 | HJ2 | SER2 | Jagged2 (CTF1) | Protein jagged-2 | Jagged2 (CTF1)_(HUMAN) | Jagged2 C-terminal fragment | Jagged 2 | Jagged2 intracellular domain | jagged 2 | Jagged2 (CTF2)_(HUMAN) | JAG2_HUMAN | Jagged2 (CTF2)

JAG2: A Non-Coding RNA Molecule as A Potential Drug Target and Biomarker

JAG2 (LGMDR27) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. JAG2 is a key regulator of the T-cell receptor (TCR) , which is a critical immune system protein that plays a crucial role in fighting off infections and diseases. In this article, we will discuss the research on JAG2 and its potential as a drug target and biomarker.

JAG2: A Non-Coding RNA Molecule

JAG2 is a non-coding RNA molecule that was first identified in 2006 using RNA interference (RNAi) technology. It is composed of 199 amino acid residues and has a calculated molecular weight of 20 kDa. JAG2 is expressed in most tissues and cells in the body and is primarily localized to the cytoplasm.

JAG2 is regulated by various factors, including DNA methylation, RNA binding protein (RBP), andmiRNA, etc. JAG2 can also be regulated by various post-transcriptional modifications, such as RNA binding protein (RBP) and miRNA, etc.

JAG2 as a Drug Target

JAG2 has been identified as a potential drug target due to its unique structure and various biological functions. One of the most significant features of JAG2 is its ability to interact with various proteins, including T-cell receptor (TCR), which is a critical immune system protein.

JAG2 has been shown to play a role in regulating the development and function of T-cells, which are a crucial part of the immune system. T-cells are responsible for recognizing and responding to foreign antigens, including viruses and cancer cells. JAG2 has has been shown to regulate the development and function of T-cells by controlling the production of T-cells, the number of T-cells in the body, and the activation of T-cells.

JAG2 has also been shown to play a role in regulating the immune response. It has been shown to regulate the production of antibodies and to control the activation and proliferation of B-cells.

JAG2 has also been shown to play a role in the regulation of cellular processes such as cell division, apoptosis, and inflammation. It has been shown to regulate the production of various cellular signaling molecules, including cell cycle progression, apoptosis, and inflammation.

JAG2 as a Biomarker

JAG2 has also been shown to be a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. JAG2 has also been shown to be overexpressed in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

For example, JAG2 has been shown to be overexpressed in various types of cancer, including breast, ovarian, and colorectal cancer. It has also been shown to be associated with various neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

JAG2 has also been shown to be associated with various autoimmune disorders, including rheumatoid arthritis, lupus, and multiple sclerosis.

Conclusion

In conclusion, JAG2 is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases. Its unique structure and various biological functions make it an attractive target for drug development. Further research is needed to fully understand the role of JAG2 in various diseases and to develop effective treatments.

Protein Name: Jagged Canonical Notch Ligand 2

Functions: Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development (By similarity)

The "JAG2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about JAG2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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JAGN1 | JAK1 | JAK2 | JAK3 | JAKMIP1 | JAKMIP1-DT | JAKMIP2 | JAKMIP2-AS1 | JAKMIP3 | JAM2 | JAM3 | JAML | Janus Kinase | JARID2 | JAZF1 | JAZF1-AS1 | JCAD | JDP2 | JHY | JKAMP | JMJD1C | JMJD1C-AS1 | JMJD4 | JMJD6 | JMJD7 | JMJD7-PLA2G4B | JMJD8 | JMY | JOSD1 | JOSD2 | JPH1 | JPH2 | JPH3 | JPH4 | JPT1 | JPT2 | JPX | JRK | JRKL | JSRP1 | JTB | JUN | JUNB | JUND | JUP | K(ATP) Channel | KAAG1 | Kainate Receptor (GluR) | Kallikrein | KALRN | KANK1 | KANK2 | KANK3 | KANK4 | KANSL1 | KANSL1-AS1 | KANSL1L | KANSL2 | KANSL3 | KANTR | KARS1 | KARS1P1 | KARS1P2 | KASH5 | KAT14 | KAT2A | KAT2B | KAT5 | KAT6A | KAT6A-AS1 | KAT6B | KAT7 | KAT8 | Katanin Complex | KATNA1 | KATNAL1 | KATNAL2 | KATNB1 | KATNBL1 | KATNBL1P6 | KATNIP | KAZALD1 | KAZN | KAZN-AS1 | KBTBD11 | KBTBD12 | KBTBD13 | KBTBD2 | KBTBD3 | KBTBD4 | KBTBD6 | KBTBD7 | KBTBD8 | KC6 | KCMF1 | KCNA1 | KCNA10 | KCNA2 | KCNA3 | KCNA4