CYB5R2: A Potential Drug Target for Xenobiotics (G51700)

Target Name: CYB5R2

NCBI ID: G51700

CYB5R2

CYB5R2: A Potential Drug Target for Xenobiotics

CYB5R2, also known as Cytochrome b5 reductase b5R.2, is a gene that encodes a protein located in the cytoplasm of all eukaryotic cells. The cytoplasm is the fluid that surrounds the nucleus and contains various organelles, including the mitochondria, endoplasmic reticulum, and peroxisomes. CYB5R2 is a member of the cytochrome b5 family of reductases, which are a group of enzymes that participate in the redox reactions that maintain the cellular oxidation-reduction balance.

The function of CYB5R2 is not well understood, but its encoded protein has been shown to be involved in the detoxification of xenobiotics, such as arsenic, lead, and cadmium, which are all toxic to humans and animals. Xenobiotics are substances that are foreign to the body and can cause damage to cells and organs if they are not removed from the body. CYB5R2 may be involved in the detoxification of these substances by converting them into less toxic forms.

CYB5R2 is also known as a potential drug target or biomarker because its involvement in the detoxification of xenobiotics makes it a promising candidate for development into a therapeutic agent. Many diseases, including cancer, are caused by the buildup of toxic substances in the body, and there is a growing interest in using drugs that can disrupt the xenobiotics levels in cells to prevent or treat these diseases. CYB5R2 may be used as a drug target by targeting the enzyme itself and inhibiting its activity.

In addition to its potential use as a drug target, CYB5R2 has also been shown to be involved in the regulation of cellular processes that are important for cell survival. Many cellular processes rely on the proper functioning of the mitochondria, which are organelles that are responsible for generating the energy that cells need to survive. The cytoplasm, which contains the mitochondria, is also involved in the regulation of many cellular processes, including the transport of nutrients and waste products within the cell.

The study of CYB5R2 and its function is still in its infancy, and much more research is needed to fully understand its role in the detoxification of xenobiotics and its potential as a drug target. However, its involvement in these processes makes it an important molecule to study and may lead to new insights into the mechanisms of cell detoxification and the development of therapeutic agents.

Protein Name: Cytochrome B5 Reductase 2

Functions: NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity). Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4-disulfophenyl]-2H tetrazolium monosodium salt (WST-1)

The "CYB5R2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CYB5R2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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