PAGE2: A Protein Interaction Target for Therapeutic Applications

Target Name: PAGE2

NCBI ID: G203569

PAGE2

PAGE2: A Protein Interaction Target for Therapeutic Applications

PAGE2 (CT16.4) is a protein that is expressed in various tissues of the human body, including the brain, pancreas, and gastrointestinal tract. It is a member of the PAGE family of proteins, which are known for their role in cell signaling and inflammation.

One of the unique features of PAGE2 is its ability to interact with other proteins and molecules. This interactivity makes PAGE2 a promising drug target, as it can be targeted by small molecules or antibodies to disrupt its functions and potentially lead to therapeutic benefits.

The PAGE2 protein is composed of 194 amino acid residues and has a calculated molecular mass of 21.1 kDa. It is expressed in a variety of tissues, including the brain, pancreas, and gastrointestinal tract, and is involved in various cellular processes.

One of the key functions of PAGE2 is its role in cell signaling. PAGE2 is a potent negative regulator of the protein kinase B-Raf-MEK-ERK signaling pathway, which is involved in many cellular processes, including cell growth, differentiation, and survival.

In addition to its role in cell signaling, PAGE2 is also involved in inflammation. PAGE2 has been shown to play a role in the development and progression of chronic inflammatory diseases, including heart disease, autoimmune diseases, and neuroinflammatory disorders.

The ability of PAGE2 to interact with other proteins and molecules makes it a promising drug target. By targeting PAGE2 with small molecules or antibodies, researchers may be able to disrupt its functions and potentially lead to therapeutic benefits. For example, one potential approach to treating neuroinflammatory disorders may be to target PAGE2 with antibodies to disrupt its interactions with other proteins and molecules involved in inflammation.

In conclusion, PAGE2 is a protein that is expressed in various tissues of the human body and is involved in a variety of cellular processes. Its ability to interact with other proteins and molecules makes it a promising drug target, as it can be targeted by small molecules or antibodies to disrupt its functions and potentially lead to therapeutic benefits. Further research is needed to fully understand the role of PAGE2 in cell signaling and inflammation, and to develop effective treatments for neuroinflammatory disorders.

Protein Name: PAGE Family Member 2

The "PAGE2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PAGE2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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