TMEM98: A Key Protein in The Immune System (G26022)

Target Name: TMEM98

NCBI ID: G26022

TMEM98

TMEM98: A Key Protein in The Immune System

TMEM98 (TMM98_HUMAN), also known as human T-cell maximum expression of MHC class I molecules, is a protein that is expressed in the human body and is responsible for the presentation of antigens to T-cells. TMEM98 is a key molecule in the immune system and plays a crucial role in the development and regulation of T-cells.

TMEM98 is a transmembrane protein that is expressed in various tissues and cells of the human body, including the skin, hair, and nails. It is a member of the transmembrane protein family, which includes proteins that span the cell membrane and extend into the cytoplasm or the space between cells. TMEM98 is characterized by its ability to form a monolayer on the cell membrane and its role in the presentation of antigens to T-cells.

TMEM98 functions as a receptor for antigens that have been processed and loaded onto its carboxylic acid-containing tail. This receptor is known as the major histocompatibility complex (MHC) class I molecules, which are a type of carbohydrate-containing protein that are expressed in the human body and are responsible for presenting antigens to T-cells. TMEM98 is able to recognize and bind to these molecules, allowing it to participate in the process of antigen presentation.

TMEM98 is also involved in the regulation of the immune response and has been shown to play a role in the development and regulation of T-cells. For example, studies have shown that TMEM98 is able to promote the growth and proliferation of T-cells and that it is involved in the regulation of the process of negative selection, which is the process by which T-cells are able to identify and destroy foreign or non-self molecules.

In addition to its role in the immune system, TMEM98 has also been shown to have potential as a drug target. Studies have shown that TMEM98 is able to interact with a variety of different drugs, including antibodies and small molecules, and that this interaction may be involved in the development of cancer. For example, researchers have shown that TMEM98 is able to interact with the drug PD-1 and that this interaction may be involved in the development of colorectal cancer.

Another potential application of TMEM98 as a drug target is its ability to be targeted with small molecules. Small molecules, also known as drugs, can be used to manipulate the activity of TMEM98 and to treat a variety of different diseases. For example, researchers have shown that small molecules can be used to inhibit the activity of TMEM98 and to prevent it from promoting the growth and proliferation of T-cells. This may be useful for treating diseases in which T-cells play a role, such as cancer.

TMEM98 is also a potential biomarker for the diagnosis and monitoring of certain diseases. For example, studies have shown that TMEM98 is able to be expressed in the blood and that its levels can be used as a marker for the diagnosis of some diseases, such as cancer. This may be useful for monitoring the effectiveness of certain treatments and for identifying potential biomarkers for diseases.

In conclusion, TMEM98 is a protein that is expressed in the human body and plays a crucial role in the immune system. It is a key molecule for the presentation of antigens to T-cells and is involved in the regulation of the immune response. TMEM98 is also a potential drug target and a potential biomarker for the diagnosis and monitoring of certain diseases. Further research is needed to fully understand the role of TMEM98 in the immune system and its potential as a drug target.

Protein Name: Transmembrane Protein 98

Functions: Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation. The secreted form promotes differentiation of T helper 1 cells (Th1)

The "TMEM98 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMEM98 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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