Understanding TMEM87B: A Potential Drug Target and Biomarker (G84910)

Target Name: TMEM87B

NCBI ID: G84910

TMEM87B

Understanding TMEM87B: A Potential Drug Target and Biomarker

TMEM87B (Tissue Membrane Model 87B) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the superfamily of transmembrane protein (SMP), which are a type of protein that spans the membrane of the cell and functions as an integral part of the cell's structure and function. TMEM87B is unique among SMP proteins because of its structure and its localization to specific tissues.

The protein is involved in various physiological processes in the body, including cell signaling, inflammation, and the regulation of ion and water transport. It is also associated with various diseases, including cancer, neurodegenerative diseases, and systemic inflammation. As a result, TMEM87B has gained significant interest as a potential drug target or biomarker.

One of the main advantages of TMEM87B as a drug target is its accessibility. The protein is expressed in a variety of tissues and can be easily targeted using various techniques, such as small interfering RNA (siRNA) screening, protein kinase inhibition, and mass spectrometry. This accessibility has allowed researchers to study its function at the molecular level and to identify potential drug targets.

Another advantage of TMEM87B is its specificity. The protein is expressed in various tissues throughout the body and is targeted to specific cell types, which has narrowed down the potential drug targets. For example, TMEM87B is expressed in the brain and is involved in the regulation of ion and water transport, which makes it a potential drug target for neurological diseases.

In addition to its accessibility and specificity, TMEM87B is also a good candidate as a biomarker for certain diseases. Its expression is known to be regulated by various factors, including blood flow, oxygenation, and signaling pathways. This makes it a potential indicator of disease status, and its levels can be used to monitor the effectiveness of treatments. For example, TMEM87B levels have been used as a biomarker to assess the efficacy of anti-inflammatory treatments in animal models of cancer.

TMEM87B is also involved in several signaling pathways that are important for its function. For example, it is involved in the regulation of ion and water transport, which is critical for maintaining the integrity of the blood-brain barrier and for maintaining the proper functioning of the brain. It is also involved in the regulation of cell signaling, which is important for the development and maintenance of tissues and organs.

In addition to its functions in signaling pathways, TMEM87B is also involved in the regulation of cellular processes that are important for its function. For example, it is involved in the regulation of the levels of various ions and molecules in the cell, including calcium, potassium, and sodium. This is important for maintaining the proper functioning of the cell and for regulating its signaling pathways.

TMEM87B is also a potential drug target because of its role in the regulation of cellular processes that are important for its function. For example, its regulation of ion and water transport is important for maintaining the integrity of the blood-brain barrier, which is critical for the proper functioning of the brain. Its regulation of cell signaling is also important for the development and maintenance of tissues and organs.

In conclusion, TMEM87B is a unique protein that is expressed in various tissues throughout the body and is involved in various physiological processes. Its accessibility, specificity, and potential as a drug target and biomarker make it an attractive target for research and development of new therapies. Further studies are needed to fully understand its function and to identify its potential as a drug and biomarker.

Protein Name: Transmembrane Protein 87B

Functions: May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN)

The "TMEM87B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TMEM87B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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