Target Name: IER3IP1
NCBI ID: G51124
Review Report on IER3IP1 Target / Biomarker Content of Review Report on IER3IP1 Target / Biomarker
IER3IP1
Other Name(s): OTTHUMP00000163487 | immediate early response 3 interacting protein 1 | Immediate early response 3 interacting protein 1 | HSPC039 | Immediate early response 3-interacting protein 1 | IR3IP_HUMAN | PRO2309 | MEDS

IER3IP1: Prolific Protein with Wide Range of Functions in The Body

IER3IP1, also known as OTTHUMP00000163487, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the IER family of proteins, which are involved in intracellular signaling. While the exact function of IER3IP1 is not yet fully understood, it is thought to play a role in the regulation of inflammation and fibrosis.

One of the key functions of IER3IP1 is its ability to regulate the activity of immune cells. In response to the presence of foreign substances in the body, IER3IP1 helps to coordinate the activation and proliferation of immune cells. This is important for maintaining the body's immune response to infections and diseases, but it can also lead to the development of autoimmune disorders.

Another function of IER3IP1 is its role in the regulation of cell death. When cells are no longer needed or are damaged, IER3IP1 helps to facilitate the process of cell death, which is important for maintaining tissue homeostasis and repair. However, imbalances in cell death can contribute to the development of diseases such as cancer.

IER3IP1 has also been shown to play a role in the regulation of cell signaling pathways. It is a known regulator of the TGF-β pathway, which is involved in the regulation of cell growth, differentiation, and survival. TGF-β is a critical signaling pathway that is involved in many aspects of development, including tissue repair and regeneration.

In addition to its role in immune and cell death regulation, IER3IP1 has also been shown to play a role in the regulation of inflammation. When the body is exposed to an infection or other harmful substances, IER3IP1 helps to coordinate the activation and function of immune cells. This is important for fighting off infections and repairing damaged tissue, but it can also lead to the development of inflammatory disorders.

Overall, IER3IP1 is a protein that is involved in a wide range of important biological processes in the body. While more research is needed to fully understand its functions and mechanisms, it is clear that IER3IP1 is a potential drug target and biomarker for a variety of diseases.

Protein Name: Immediate Early Response 3 Interacting Protein 1

Functions: Regulator of endoplasmic reticulum secretion that acts as a key determinant of brain size (PubMed:33122427). Required for secretion of extracellular matrix proteins (PubMed:33122427). Required for correct brain development by depositing sufficient extracellular matrix proteins for tissue integrity and the proliferation of neural progenitors (PubMed:33122427). Acts as a regulator of the unfolded protein response (UPR) (By similarity)

The "IER3IP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about IER3IP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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