Target Name: TENM1
NCBI ID: G10178
Review Report on TENM1 Target / Biomarker Content of Review Report on TENM1 Target / Biomarker
TENM1
Other Name(s): tenascin-M1 | Protein Odd Oz/ten-m homolog 1 | Teneurin-1 | Ten-1 ICD | teneurin 1 | TEN-M1 | Teneurin-1 (isoform 1) | Teneurin-1 (isoform 2) | TNM1 | Teneurin-1 (isoform 3) | teneurin transmembrane protein 1 | ODZ3 | protein Odd Oz/ten-m homolog 1 | ODZ1 | TEN1 | TENM1 variant 3 | Teneurin 1 | Ten-1 intracellular domain | OTTHUMP00000024333 | Odz (odd Oz/ten-m, Drosophila) homolog 3 | odz, odd Oz/ten-m homolog 1(Drosophila) | Tenascin M1 | Tenascin-M1 | Teneurin C-terminal-associated peptide | IDten-1 | odz (odd Oz/ten-m, Drosophila) homolog 3 | Teneurin transmembrane protein 1, transcript variant 2 | TEN1_HUMAN | Teneurin transmembrane protein 1, transcript variant 1 | Ten-m1 | Teneurin transmembrane protein 1, transcript variant 3 | Ten-1 extracellular domain | tenascin M1 | TENM1 variant 2 | odz, odd Oz/ten-m homolog 1 | Teneurin transmembrane protein 1 | TENM1 variant 1 | TNM | TCPA-1 | Ten-1 ECD | ten-1 | Ten-1

TENM1: A Potential Drug Target and Biomarker for ALS-Like Neurodegenerative Diseases

Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, are the leading causes of disability and death worldwide. These conditions are characterized by the progressive loss of brain cells, leading to a range of symptoms that include cognitive decline, muscle weakness, paralysis, and loss of independence. Despite advances in neuroscience and disease treatment, there is currently no cure for these conditions. Therefore, the development of new treatments and biomarkers is of great interest.

TENM1: A Potential Drug Target and Biomarker

TENM1, short for Tau-associated neurodegeneration-1, is a protein that is expressed in the brain and is associated with various neurodegenerative diseases. The protein is a neurotransmitter acetylator, which means it modulates the levels of neurotransmitters in the brain. TENM1 has been shown to play a role in the development and progression of neurodegenerative diseases, including ALS-like conditions.

Potential Therapeutic Strategies

The identification of TENM1 as a potential drug target provides new avenues for therapeutic intervention. One approach is to target TENM1 directly with small molecules or antibodies to reduce its levels in the brain and improve neurodegeneration. Another approach is to target TENM1 with drugs that modulate its activity, such as those that increase levels of neurotransmitters or those that inhibit its function.

Biomarkers

While the development of new treatments for neurodegenerative diseases is an exciting endeavor, the identification of biomarkers is critical for evaluating the effectiveness of these treatments. TENM1 is a potential biomarker for neurodegenerative diseases, as its levels are affected by various neurotransmitters, including dopamine, a neurotransmitter that is involved in motor function and behavior.

Importance of TENM1 as a Biomarker

The identification of TENM1 as a potential biomarker for neurodegenerative diseases has significant implications for the development of new treatments. If TENM1 can be accurately measured and correlated with disease severity, it could be used as a biomarker to evaluate the effectiveness of new treatments. This would allow for more efficient and effective use of medical resources, as researchers could more accurately predict which treatments are most likely to be effective and which are not.

In addition, the identification of TENM1 as a biomarker could lead to the development of new diagnostic tests for neurodegenerative diseases. This could have a significant impact on the field of neuroscience and clinical medicine, as accurate diagnosis is essential for the development of effective treatments.

Conclusion

TENM1 is a protein that is associated with various neurodegenerative diseases, including ALS-like conditions. Its potential as a drug target and biomarker has significant implications for the development of new treatments for these conditions. Further research is needed to fully understand the role of TENM1 in neurodegenerative diseases and to develop effective treatments.

Protein Name: Teneurin Transmembrane Protein 1

Functions: Involved in neural development, regulating the establishment of proper connectivity within the nervous system. May function as a cellular signal transducer (By similarity)

The "TENM1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TENM1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TENM2 | TENM2-AS1 | TENM3 | TENM3-AS1 | TENM4 | TENT2 | TENT4A | TENT4B | TENT5A | TENT5B | TENT5C | TENT5C-DT | TENT5D | TEP1 | TEPP | TEPSIN | TERB1 | TERB2 | TERC | TERF1 | TERF1P3 | TERF2 | TERF2IP | TERLR1 | TERT | TES | TESC | TESK1 | TESK2 | TESMIN | TESPA1 | TET1 | TET2 | TET2-AS1 | TET3 | Tetraspanin | TEX10 | TEX101 | TEX11 | TEX12 | TEX13A | TEX13B | TEX13C | TEX14 | TEX15 | TEX19 | TEX2 | TEX21P | TEX22 | TEX26 | TEX261 | TEX264 | TEX28 | TEX29 | TEX30 | TEX33 | TEX35 | TEX36 | TEX36-AS1 | TEX37 | TEX38 | TEX41 | TEX43 | TEX44 | TEX45 | TEX46 | TEX47 | TEX48 | TEX49 | TEX50 | TEX52 | TEX53 | TEX55 | TEX56P | TEX9 | TF | TFAM | TFAMP1 | TFAP2A | TFAP2A-AS1 | TFAP2A-AS2 | TFAP2B | TFAP2C | TFAP2D | TFAP2E | TFAP4 | TFB1M | TFB2M | TFCP2 | TFCP2L1 | TFDP1 | TFDP1P2 | TFDP2 | TFDP3 | TFE3 | TFEB | TFEC | TFF1 | TFF2 | TFF3