Target Name: TEP1
NCBI ID: G7011
Review Report on TEP1 Target / Biomarker Content of Review Report on TEP1 Target / Biomarker
TEP1
Other Name(s): VAULT2 | Telomerase protein 1 | Telomerase protein component 1 (isoform 1) | TROVE1 | telomerase associated protein 1 | TLP1 | Telomerase-associated protein 1 | TEP1 variant 1 | Telomerase protein component 1 | TP1 | p80 telomerase homolog | telomerase protein 1 | TEP1_HUMAN | p80 Telomerase homolog | TROVE domain family, member 1 | p240 | Telomerase associated protein 1, transcript variant 1

Understanding TEP1: A Potential Drug Target for Cancer and Other Diseases

TEP1 (Vault2) is a protein that is expressed in various tissues throughout the body, including the brain. It is a key regulator of the cell cycle, and is involved in the development and progression of many diseases, including cancer.

Recent studies have identified TEP1 as a potential drug target (or biomarker) for the treatment of various diseases, including cancer. One of the main reasons for its potential as a drug target is its involvement in the regulation of cell division and the cell cycle.

In cancer, abnormal cell division and the failure of the cell cycle are key drivers of the disease. TEP1 helps to regulate the cell cycle by controlling the movement of chromosomes along the DNA in the cell. This regulation is critical for the proper development and progression of tissues and for the formation of new organisms.

In addition to its role in cell division, TEP1 is also involved in the regulation of cell growth and the response to stimuli. This is important for maintaining tissue homeostasis and for the development of tissues and organs.

As a potential drug target, TEP1 is being studied for its ability to inhibit the activity of various enzymes that are involved in the cell cycle and in the regulation of cell growth. This is done to prevent the growth and spread of cancer cells and to promote the growth and development of healthy tissues.

One of the main challenges in studying TEP1 as a drug target is its complex structure and the difficulty in predicting its interactions with small molecules. To overcome this challenge, researchers have used a variety of techniques to study its behavior, including biochemical, cellular, and structural studies.

In biochemical studies, researchers have used a variety of techniques to determine the activity of TEP1 and its interactions with small molecules. For example, they have used cell-based assays to determine the effects of small molecules on TEP1 expression and activity. They have also used in vitro assays to study the effects of small molecules on the structure and function of TEP1.

In cellular studies, researchers have used a variety of techniques to study the behavior of TEP1 and its interactions with small molecules. For example, they have used live cell imaging techniques to visualize the effects of small molecules on TEP1 expression and activity. They have also used techniques such as RNA interference and CRISPR/Cas9 to study the effects of small molecules on TEP1 gene expression.

In structural studies, researchers have used a variety of techniques to study the structure and function of TEP1. For example, they have used X-ray crystallography to determine the crystal structure of TEP1 and to study its interactions with small molecules. They have also used electron microscopy to study the structure and function of TEP1 at the atomic level.

Overall, the studies on TEP1 have provided a significant understanding of its role in the regulation of the cell cycle and its potential as a drug target. Further research is needed to fully understand its behavior and its potential as a drug.

Protein Name: Telomerase Associated Protein 1

Functions: Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini (PubMed:19179534). Also a component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport (By similarity). Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC (By similarity)

The "TEP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TEP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

TEPP | TEPSIN | TERB1 | TERB2 | TERC | TERF1 | TERF1P3 | TERF2 | TERF2IP | TERLR1 | TERT | TES | TESC | TESK1 | TESK2 | TESMIN | TESPA1 | TET1 | TET2 | TET2-AS1 | TET3 | Tetraspanin | TEX10 | TEX101 | TEX11 | TEX12 | TEX13A | TEX13B | TEX13C | TEX14 | TEX15 | TEX19 | TEX2 | TEX21P | TEX22 | TEX26 | TEX261 | TEX264 | TEX28 | TEX29 | TEX30 | TEX33 | TEX35 | TEX36 | TEX36-AS1 | TEX37 | TEX38 | TEX41 | TEX43 | TEX44 | TEX45 | TEX46 | TEX47 | TEX48 | TEX49 | TEX50 | TEX52 | TEX53 | TEX55 | TEX56P | TEX9 | TF | TFAM | TFAMP1 | TFAP2A | TFAP2A-AS1 | TFAP2A-AS2 | TFAP2B | TFAP2C | TFAP2D | TFAP2E | TFAP4 | TFB1M | TFB2M | TFCP2 | TFCP2L1 | TFDP1 | TFDP1P2 | TFDP2 | TFDP3 | TFE3 | TFEB | TFEC | TFF1 | TFF2 | TFF3 | TFG | TFIID Basal Transcription Factor Complex | TFIIIC2 complex | TFIP11 | TFIP11-DT | TFPI | TFPI2 | TFPT | TFR2 | TFRC | TG | TGDS | TGFA | TGFA-IT1