Target Name: MKRN3
NCBI ID: G7681
Review Report on MKRN3 Target / Biomarker Content of Review Report on MKRN3 Target / Biomarker
MKRN3
Other Name(s): ZFP127 | D15S9 | RING-type E3 ubiquitin transferase makorin-3 | zinc finger protein 127 | MKRN3_HUMAN | Makorin-3 | CPPB2 | OTTHUMP00000159436 | MGC88288 | Probable E3 ubiquitin-protein ligase makorin-3 | makorin ring finger protein 3 | RING finger protein 63 | Zinc finger protein 127 | ZNF127 | Makorin ring finger protein 3 | RNF63

MKRN3 (ZFP127) as A Cancer Treatment Potential Drug Target

MKRN3 (ZFP127) is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer. The gene is located on chromosome 6 and encodes for a protein known as ZFP127. ZFP127 is a transcription factor that plays a role in the regulation of gene expression and has been shown to be involved in a number of cellular processes, including cell growth, differentiation, and survival.

One of the key features of ZFP127 is its ability to form a complex with other transcription factors, including NF-kappa-B, p53, andCREB. This interaction between ZFP127 and these transcription factors is thought to play a role in the regulation of gene expression and the control of cellular processes such as cell growth, differentiation, and survival.

In addition to its role in transcription, ZFP127 has also been shown to play a role in the regulation of protein translation, which is the process by which proteins are synthesized from their amino acid sequence. This interaction between ZFP127 and protein translation factors is thought to be important for the regulation of cellular processes such as cell growth and survival.

The potential drug target status of ZFP127 is based on several factors. First, the gene has been shown to be involved in the regulation of cellular processes that are often disrupted in cancer, such as cell growth, differentiation, and survival. Second, the gene has been shown to play a role in the regulation of transcription, which is a critical process in the regulation of gene expression and the development of cancer.

Finally, ZFP127 has also been shown to interact with other transcription factors, including NF-kappa-B, p53, andCREB. This interaction with these transcription factors is thought to play a role in the regulation of gene expression and the development of cancer.

In conclusion, MKRN3 (ZFP127) is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer. The gene is involved in the regulation of cellular processes such as cell growth, differentiation, and survival and has been shown to interact with other transcription factors that play a role in the development of cancer. Further research is needed to determine the full scope of ZFP127's potential as a drug target or biomarker.

Protein Name: Makorin Ring Finger Protein 3

Functions: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins

The "MKRN3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MKRN3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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