MMP19: Regulation of ECM Synthesis and Wound Healing (G4327)

Target Name: MMP19

NCBI ID: G4327

MMP19

MMP19: Regulation of ECM Synthesis and Wound Healing

Matrix metalloproteinase (MMP) 19 (MMP19) is a protein that is expressed in various tissues throughout the body, including the extracellular matrix (ECM), bone, and connective tissue. MMP19 is a member of the MMP family of proteins, which are involved in the degradation of extracellular matrix components.

MMP19 is involved in the regulation of cellular processes that are critical for tissue growth, wound healing, and inflammation. MMP19 has been shown to play a key role in the regulation of matrix remodeling, which is the process by which new cells are added to a wound or tissue and the old cells are removed. MMP19 helps to ensure that the matrix is properly prepared for the arrival of new cells and allows for the efficient disposal of old cells.

One of the key functions of MMP19 is its ability to stimulate the production of extracellular matrix (ECM) components. ECM is a complex mixture of proteins that is involved in providing support, structure, and mechanical properties to tissues. MMP19 has been shown to stimulate the production of ECM components by promoting the activity of fibroblasts, which are cells that produce the protein collagen.

In addition to its role in ECM synthesis, MMP19 is also involved in the regulation of the activity of other cell types. For example, MMP19 has been shown to promote the migration of cells, such as cancer cells, and to regulate the activity of cells involved in the immune response.

MMP19 has also been shown to play a role in the regulation of inflammation. During wound healing, MMP19 has been shown to contribute to the production of pro-inflammatory cytokines, which can help to attract immune cells to the site of the wound and promote the healing process.

Despite its many functions, MMP19 is still an poorly understood protein. little is known about the precise mechanism by which MMP19 regulates ECM synthesis, and the full extent of its role in wound healing and inflammation.

In conclusion, MMP19 is a protein that is involved in a wide range of cellular processes, including ECM synthesis, migration, and inflammation. Its functions make it an attractive target for drug development, with potential applications in the treatment of a variety of diseases. Further research is needed to fully understand the precise mechanism by which MMP19 functions and to explore its potential as a drug or biomarker.

Protein Name: Matrix Metallopeptidase 19

Functions: Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin

The "MMP19 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MMP19 comprehensively, including but not limited to:
•   general information;
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•   protein biological mechanisms;
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•   expression level;
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•   pharmacochemistry experiments;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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