MMP7: A Protein Regulator of The Extracellular Matrix and Cell-to-Matrix Interactions

Target Name: MMP7

NCBI ID: G4316

MMP7

MMP7: A Protein Regulator of The Extracellular Matrix and Cell-to-Matrix Interactions

MMP7, or matrix-accessible remote pH 7, is a protein that is expressed in various tissues throughout the body. It is a key regulator of the extracellular matrix (ECM), which is a complex tissue matrix that is essential for cell-to-cell and cell-to-surface interactions. MMP7 is involved in the regulation of cell adhesion, migration, and invasion, as well as in the production of signaling molecules that regulate the ECM.

MMP7 has been identified as a potential drug target for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role in these diseases has led to the development of new therapeutic strategies, such as inhibiting MMP7 activity to treat these conditions.

One of the key challenges in studying MMP7 is its complex biochemical and cellular interactions. MMP7 is a member of the large family of serine proteases, known as matrix-remodeling proteins (MRP), and it functions as a key regulator of the ECM. The ECM is a complex tissue matrix that is composed of a variety of proteins, including collagen, elastin, and glycosaminoglycans, which are involved in providing structure, mechanical properties, and signaling molecules to cells. MMP7 plays a critical role in the regulation of these proteins, as well as in the production of other ECM components.

MMP7 is involved in the regulation of several different processes that are essential for ECM structure and function. One of its key functions is the regulation of collagen synthesis and degradation. Collagen is a protein that is involved in the structure and mechanical properties of the ECM, and it is a key component of the extracellular matrix. MMP7 is involved in the regulation of collagen synthesis by promoting its production and by inhibiting its degradation. This allows MMP7 to play a critical role in the regulation of cell-to-ECM interactions and in the development of tissue structure.

MMP7 is also involved in the regulation of the production of other ECM components. For example, MMP7 is involved in the production of hyaluronic acid, a component of the extracellular matrix that is involved in cell-to-matrix interactions. Hyaluronic acid is produced by the cells and is then incorporated into the ECM by MMP7. This allows MMP7 to play a critical role in the regulation of cell-to-ECM interactions and in the development of tissue structure.

In addition to its functions in regulating ECM structure and function, MMP7 is also involved in the regulation of cellular processes. For example, MMP7 is involved in the regulation of cell adhesion and migration. It does this by participating in the formation of tight junctions, which are specialized junctions that are involved in the regulation of cell-to-cell interactions, as well as by participating in the regulation of cell migration. MMP7 is also involved in the regulation of cell signaling pathways, including the TGF-β pathway, which is involved in the regulation of cell growth, differentiation, and survival.

MMP7 has been identified as a potential drug target for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role in these diseases has led to the development of new therapeutic strategies, such as inhibiting MMP7 activity to treat these conditions. One of the key challenges in studying MMP7 is its complex biochemical and cellular interactions, which make it difficult to understand its mechanisms of action. Further research is needed to fully understand the role of MMP7 in these diseases and to develop new therapeutic strategies.

Protein Name: Matrix Metallopeptidase 7

Functions: Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase

The "MMP7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MMP7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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