MOB1B: A Promising Drug Target and Biomarker (G92597)

Target Name: MOB1B

NCBI ID: G92597

MOB1B

MOB1B: A Promising Drug Target and Biomarker

MOB1B, or Mob1B, is a protein that is expressed in various tissues throughout the body, including the brain, heart, and blood vessels. It is a key regulator of cell growth, differentiation, and survival, and is involved in many important cellular processes.

One of the most promising aspects of MOB1B is its potential as a drug target. MOB1B has been shown to play a role in a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role in these conditions makes it an attractive target for drug developers.

One of the key features of MOB1B that makes it a promising drug target is its structure. MOB1B is a transmembrane protein, which means that it spans the cell membrane and is involved in various cellular processes that occur on both sides of the membrane. This allows MOB1B to interact with a wide range of molecules, including drugs, ions, and other proteins.

In addition to its structural features, MOB1B is also a good candidate for a drug target because of its gene expression profile. MOB1B is highly expressed in many tissues and has been shown to be involved in a wide range of cellular processes, including cell growth, differentiation, and survival. This suggests that MOB1B is a good candidate for a drug target because it is involved in important cellular processes that can be targeted by drugs.

Another factor that makes MOB1B an attractive drug target is its role in the development of certain diseases. For example, MOB1B has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. This suggests that MOB1B may be a useful target for drugs that are designed to treat these conditions.

In addition to its potential as a drug target, MOB1B is also a potential biomarker. Its role in the regulation of cell growth, differentiation, and survival makes it an attractive candidate for use as a biomarker for a variety of diseases. For example, MOB1B has been shown to be involved in the regulation of cancer cell growth, and has been used as a biomarker for cancer.

Another potential use for MOB1B as a drug target is its role in the regulation of cellular signaling pathways. MOB1B has been shown to be involved in a wide range of signaling pathways, including the regulation of cell growth, differentiation, and survival. This suggests that MOB1B may be a useful target for drugs that are designed to modulate these signaling pathways.

In conclusion, MOB1B is a protein that is expressed in various tissues throughout the body and is involved in many important cellular processes. Its structure, gene expression profile, and role in the development of certain diseases make it an attractive candidate for a drug target. In addition, MOB1B may also be a useful biomarker for a variety of diseases. Further research is needed to fully understand the role of MOB1B in cellular processes and its potential as a drug and biomarker.

Protein Name: MOB Kinase Activator 1B

Functions: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L

The "MOB1B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MOB1B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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