Target Name: MOB3B
NCBI ID: G79817
Review Report on MOB3B Target / Biomarker Content of Review Report on MOB3B Target / Biomarker
MOB3B
Other Name(s): mps one binder kinase activator-like 2B | MOB1D | FLJ13204 | mob1 homolog 2b | Monopolar spindle 1 binding, MOB1, domain containing | Protein Mob3B | MOBKL2B | FLJ23916 | MOB kinase activator-like 2B | MOB1, Mps One Binder kinase activator-like 2B | MOB kinase activator 3B | MGC32960 | Mob1 homolog 2b | C9orf35 | monopolar spindle 1 binding, MOB1, domain containing | MOB3B_HUMAN | Mps one binder kinase activator-like 2B

MOB3B: A Potential Drug Target for Cancer

MOB3B, also known as Mps one binder kinase activator-like 2B, is a protein that is expressed in various tissues and cells throughout the body. It has been shown to play a role in the regulation of cell proliferation, differentiation, and survival. As a result, MOB3B has been identified as a potential drug target and a biomarker for various diseases, including cancer.

The MOB3B protein is a key regulator of the TGF-β pathway, which is a well-known signaling pathway that plays a role in the development and maintenance of tissues and organs. During TGF-β signaling, the protein Smad4 is activated and forms a complex with the transcription factor Smad2. This complex then activates the transcription factor transcription factor-like 3 (TALF3), which is involved in the regulation of cell proliferation and differentiation.

MOB3B has been shown to play a role in the regulation of TGF-β signaling by interacting with the transcription factor Smad2. This interaction between MOB3B and Smad2 allows for the regulation of TGF-β signaling and the downstream regulation of cell proliferation and differentiation.

In addition to its role in TGF-β signaling, MOB3B has also been shown to play a role in the regulation of cell survival. Studies have shown that MOB3B has been shown to play a role in the regulation of cell survival by interacting with the protein Bcl-2. This interaction between MOB3B and Bcl-2 allows for the regulation of cell survival and the ability to escape from apoptosis.

MOB3B has also been shown to play a role in the regulation of cell differentiation. Studies have shown that MOB3B has been shown to play a role in the regulation of cell differentiation by interacting with the protein Sox2. This interaction between MOB3B and Sox2 allows for the regulation of cell differentiation and the ability to maintain a stem cell-like state.

MOB3B has also been shown to play a role in the regulation of cellular processes such as cell adhesion, migration and invasion. Studies have shown that MOB3B interacts with several proteins including E-cadherin, N-cadherin, and vimentin, which are involved in cell adhesion and migration. This interaction between MOB3B and these proteins allows for the regulation of cellular processes that are critical for the development and progression of cancer.

MOB3B has also been shown to play a role in the regulation of apoptosis. Studies have shown that MOB3B has been shown to play a role in the regulation of apoptosis by interacting with the protein p53. This interaction between MOB3B and p53 allows for the regulation of apoptosis and the ability to prevent it from occurring.

MOB3B has also been shown to play a role in the regulation of cell cycle progression. Studies have shown that MOB3B interacts with the protein cyclin D1, which is involved in the regulation of cell cycle progression. This interaction between MOB3B and Cyclin D1 allows for the regulation of cell cycle progression and the ability to maintain a normal cell cycle.

MOB3B has also been shown to play a role in the regulation of angiogenesis. Studies have shown that MOB3B interacts with the protein FAK, which is involved in the regulation of angiogenesis. This interaction between MOB3B and FAK allows for the regulation of angiogenesis and the ability to maintain blood vessel formation.

In addition to its role in TGF-β signaling, MOB3B has also been shown to play a role in the regulation of cell survival, differentiation, and apoptosis. As a result, MOB3B has been identified as a potential drug target and a biomarker for various diseases, including cancer.

MOB3B has been shown to play a role in the regulation of cancer cell proliferation. Studies have shown that MOB3B has been shown to promote the growth and proliferation of cancer cells. This promotion of cancer cell proliferation by MOB3B makes it a potential target for cancer therapies.

MOB3B has also been shown to play a role in the regulation of cancer cell survival. Studies have shown that MOB3B has been shown to promote the survival of cancer cells by interacting with the

Protein Name: MOB Kinase Activator 3B

Functions: Modulates LATS1 expression in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis

The "MOB3B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MOB3B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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