Target Name: SLMAP
NCBI ID: G7871
Review Report on SLMAP Target / Biomarker Content of Review Report on SLMAP Target / Biomarker
SLMAP
Other Name(s): Sarcolemmal membrane-associated protein (isoform b) | SLMAP_HUMAN | Sarcolemmal membrane-associated protein | SLAP | MGC138760 | MGC138761 | KIAA1601 | Sarcolemma associated protein, transcript variant 2 | FLJ42206 | SLMAP variant 2 | Sarcolemmal-associated protein | sarcolemma associated protein | OTTHUMP00000165233

SLMAP: A Protein Involved in Cell Adhesion, Adenosine Production and Inflammation

SLMAP, or Sarcolemmal membrane-associated protein (isoform b), is a protein that is expressed in various tissues throughout the body, including the brain, heart, lungs, and kidneys. It is a member of the family of transmembrane proteins, which means that it spans the cell membrane and is involved in various signaling processes.

SLMAP is a 21-kDa protein that is composed of two distinct isoforms, isoform A and isoform B. These isoforms are produced by alternative splicing of the same gene, and they differ in their length and their ability to interact with certain signaling molecules. Isoform A is the full-length protein, and it consists of 1,204 amino acids. Isoform B is a truncated form that consists of only 68 amino acids.

SLMAP is involved in various signaling pathways, including the regulation of cell adhesion, the production of adenosine, and the regulation of inflammation. It is also involved in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

One of the main functions of SLMAP is its role in cell adhesion. SLMAP is involved in the formation of tight junctions, which are specialized junctions that are responsible for maintaining the integrity of the intercellular barrier. It does this by playing a role in the regulation of the cytoskeleton and the cytoplasm.

SLMAP is also involved in the production of adenosine, which is a signaling molecule that plays a role in various physiological processes, including immune response, pain perception, and blood pressure. It is produced by cells in the immune system and other tissues, and it can interact with various signaling molecules to regulate these processes.

In addition to its role in cell adhesion and adenosine production, SLMAP is also involved in the regulation of inflammation. It is has been shown to play a role in the regulation of various immune responses, including the regulation of T cell responses. It is also involved in the regulation of inflammation, which is critical for the development of various diseases.

SLMAP is also involved in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. For example, studies have shown that SLMAP is involved in the development of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. It is also involved in the regulation of various signaling pathways that are involved in the development of cancer, including the regulation of cell proliferation and the production of pro-inflammatory cytokines.

SLMAP is also a potential drug target and biomarker for various diseases. For example, studies have shown that SLMAP is involved in the regulation of various signaling pathways that are involved in the development of cancer, including the regulation of cell proliferation and the production of pro -inflammatory cytokines. This makes it a potential target for cancer therapies that target these pathways. In addition, SLMAP has also been shown to be involved in the regulation of various signaling pathways that are involved in the development of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. This makes it a potential target for therapies that target these diseases.

In conclusion, SLMAP is a protein that is involved in various signaling pathways and is expressed in various tissues throughout the body. It is a potential drug target and biomarker for various diseases, including cancer and neurodegenerative diseases. Further research is needed to fully understand the role of SLMAP in these processes and to develop effective therapies that target it.

Protein Name: Sarcolemma Associated Protein

Functions: May play a role during myoblast fusion

The "SLMAP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLMAP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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