Kinesin Family Member 18A: A Potential Drug Target and Biomarker

Target Name: KIF18A

NCBI ID: G81930

KIF18A

Kinesin Family Member 18A: A Potential Drug Target and Biomarker

Kinesin family member 18A (KIF18A) is a protein that plays a critical role in the structure and function of the mitochondria, which are responsible for generating the energy that cells require for their daily operations. Mitochondria are organelles that are found in the cells of all eukaryotes, and they are responsible for the production of the ATP, or adenosine triphosphate, which is the primary energy source for the cell.

KIF18A is a member of the kinesin family, which is a group of proteins that are involved in the movement of organelles within the cell. The kinesin family includes several different proteins, including KIF17A, KIF18B, KIF19A, and KIF20A, and each of these proteins plays a unique role in the structure and function of the mitochondria.

One of the key functions of KIF18A is its role in the proper functioning of the mitochondria. The mitochondria are organelles that are found in the cells of all eukaryotes, and they are responsible for the production of the ATP, or adenosine triphosphate, which is the primary energy source for the cell. KIF18A is involved in the proper functioning of the mitochondria by helping to regulate the movement of organelles within the cell.

In addition to its role in regulating the functioning of the mitochondria, KIF18A is also involved in the development and progression of various diseases. For example, KIF18A has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Additionally, KIF18A has also been shown to be involved in the development of cancer, and it is thought to play a role in the development of various types of cancer.

Given the important role that KIF18A plays in the structure and function of the mitochondria, as well as its involvement in the development and progression of various diseases, it is a promising candidate for drug targeting. By blocking the activity of KIF18A, researchers may be able to develop new treatments for a variety of conditions. Additionally, KIF18A may also be used as a biomarker to diagnose and monitor certain diseases.

In conclusion, KIF18A is a protein that plays a critical role in the structure and function of the mitochondria, as well as being involved in the development and progression of various diseases. As a result, it is a promising candidate for drug targeting and as a biomarker for certain diseases. Further research is needed to fully understand the role of KIF18A in the cell and to develop new treatments and biomarkers for it.

Protein Name: Kinesin Family Member 18A

Functions: Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression

The "KIF18A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KIF18A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets