PUDP: Potential Drug Target Or Biomarker for Neurodegenerative Diseases

Target Name: PUDP

NCBI ID: G8226

PUDP

Other Name(s): haloacid dehalogenase-like hydrolase domain-containing protein 1A | haloacid dehalogenase-like hydrolase domain containing 1 | 5'-PsiMPase | haloacid dehalogenase-like hydrolase domain containing 1A |

PUDP: Potential Drug Target Or Biomarker for Neurodegenerative Diseases

PUDP (Haloacid Dehalogenase-Like Hydrolase Domain-Containing Protein 1A) is a protein that belongs to the Haloacid Dehalogenase-Like Hydrolase (HAL) family. This family is known for their ability to detoxify halogenated compounds, which are often found in environmental and human samples.

PUDP is a 185 amino acid protein that is expressed in various tissues throughout the body. It is primarily localized to the cytoplasm and has been shown to be involved in the detoxification of a variety of halogenated compounds, including arsenic, selenium, and thallium.

One of the unique features of PUDP is its ability to induce apoptosis (programmed cell death) in cells. This is accomplished through the production of reactive oxygen species (ROS), which can damage cellular components and contribute to the development of oxidative stress.

In addition to its ability to induce apoptosis, PUDP has also been shown to play a role in the regulation of cellular processes such as cell adhesion, migration, and invasion. It is also involved in the development of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

Due to its involvement in these processes, PUDP has potential as a drug target or biomarker for a variety of diseases. For example,PUDP has been shown to be involved in the development of neurodegenerative diseases, and may be a potential target for therapies aimed at preventing or treating these conditions.

In addition to its potential as a drug or biomarker, PUDP also has important practical applications in various fields, such as environmental science and food safety. For example,PUDP can be used to detect and remove halogenated compounds from water and other environmental samples, making it an important tool for environmental protection.

In conclusion, PUDP is a protein with significant potential as a drug target or biomarker for a variety of diseases. Its ability to induce apoptosis, as well as its involvement in the regulation of cellular processes, make it an attractive target for researchers seeking to develop new treatments for neurodegenerative diseases. Additionally,PUDP's ability to detect and remove halogenated compounds from water and other environmental samples makes it an important tool for environmental protection.

Protein Name: Pseudouridine 5'-phosphatase

Functions: Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine

The "PUDP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PUDP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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