Target Name: KLRC4
NCBI ID: G8302
Review Report on KLRC4 Target / Biomarker Content of Review Report on KLRC4 Target / Biomarker
KLRC4
Other Name(s): killer cell lectin like receptor C4 | natual killer cell group 2-F | Natual killer cell group 2-F | NKG2F | FLJ78582 | Killer cell lectin like receptor C4 | NKG2-F-activating NK receptor | FLJ17759 | NK cell receptor F | killer cell lectin-like receptor subfamily C, member 4 | NKG2F_HUMAN | NKG2-F | NKG2-F type II integral membrane protein

KLRC4: A Potential Drug Target for Cancer and Infectious Diseases

Killer cell lectin-like receptor C4 (KLRC4) is a protein that is expressed in various cell types, including natural killer cells, macrophages, and dendritic cells. It is a type of transmembrane protein that is characterized by the presence of a extracellular domain, a transmembrane domain, and an intracellular domain. KLRC4 is involved in various cellular processes, including immune responses and inflammation.

One of the unique features of KLRC4 is its ability to recognize and interact with various types of bacteria, as well as viruses and other pathogens. This is accomplished through the use of the Fc portion of the protein, which consists of a high-affinity glycosylation site that is able to interact with the surface of these pathogens. This ability to recognize and interact with pathogens is what makes KLRC4 a potential drug target.

In addition to its role in immune responses, KLRC4 is also involved in various cellular processes that are important for maintaining tissue homeostasis. For example, it is involved in the regulation of cell adhesion, as well as the production of various signaling molecules that are involved in cell signaling pathways.

KLRC4 is also known for its role in the development and progression of various diseases, including cancer. Studies have shown that KLRC4 is often expressed in various types of cancer, and that it is involved in the development of cancer cell stemness. This suggests that KLRC4 may be a useful biomarker for the diagnosis and treatment of cancer.

Another potential use for KLRC4 is its potential as a therapeutic agent. By targeting the Fc portion of the protein, it is possible to modulate the activity of KLRC4 and enhance its ability to interact with pathogens and other molecules. This suggests that KLRC4 may be an effective target for the development of vaccines, diagnostic tools, and therapeutic agents for a variety of diseases.

In conclusion, KLRC4 is a protein that is involved in various cellular processes that are important for immune responses and tissue homeostasis. Its ability to recognize and interact with pathogens makes it a potential drug target, and its role in the development and progression of cancer makes it a potential biomarker. Further research is needed to fully understand the function and potential uses of KLRC4, and to develop safe and effective therapies for the treatment of various diseases.

Protein Name: Killer Cell Lectin Like Receptor C4

Functions: May play a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells

The "KLRC4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KLRC4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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KLRC4-KLRK1 | KLRD1 | KLRF1 | KLRF2 | KLRG1 | KLRG2 | KLRK1 | KLRK1-AS1 | KMO | KMT2A | KMT2B | KMT2C | KMT2CP4 | KMT2D | KMT2E | KMT2E-AS1 | KMT5A | KMT5B | KMT5C | KNCN | KNDC1 | KNG1 | KNL1 | KNOP1 | KNOP1P5 | KNSTRN | KNTC1 | KPNA1 | KPNA2 | KPNA3 | KPNA4 | KPNA5 | KPNA6 | KPNA7 | KPNB1 | KPNB1-DT | KPRP | KPTN | KRAS | KRASP1 | KRBA1 | KRBA2 | KRBOX1 | KRBOX1-AS1 | KRBOX4 | KRBOX5 | KRCC1 | KREMEN1 | KREMEN2 | KRI1 | KRIT1 | KRR1 | KRT1 | KRT10 | KRT10-AS1 | KRT12 | KRT126P | KRT13 | KRT14 | KRT15 | KRT16 | KRT16P1 | KRT16P2 | KRT16P3 | KRT16P6 | KRT17 | KRT17P1 | KRT17P2 | KRT17P3 | KRT17P5 | KRT17P7 | KRT18 | KRT18P1 | KRT18P12 | KRT18P13 | KRT18P16 | KRT18P17 | KRT18P19 | KRT18P22 | KRT18P23 | KRT18P24 | KRT18P27 | KRT18P28 | KRT18P29 | KRT18P31 | KRT18P33 | KRT18P34 | KRT18P4 | KRT18P40 | KRT18P41 | KRT18P42 | KRT18P44 | KRT18P48 | KRT18P49 | KRT18P5 | KRT18P50 | KRT18P51 | KRT18P55 | KRT18P59 | KRT18P6