KRT18P27: A Potential Drug Target and Biomarker (G390418)

KRT18P27: A Potential Drug Target and Biomarker

Keratin 18 (K18) pseudogene 27 (KRT18P27) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. Its unique structure and expression patterns have made it an attractive target for researchers to study, and its potential utility as a therapeutic agent has piqued the interest of pharmaceutical companies and researchers alike.

The K18 gene is a member of the keratin gene family, which is responsible for the production of the proteins that make up the hair and nails. In humans, the K18 gene encodes a 27-base pair RNA molecule that is expressed in various tissues and cells of the body.

KRT18P27 has been shown to play a critical role in the regulation of cell growth and differentiation. It has been shown to be involved in the regulation of cell cycle progression, and has been linked to the development and progression of various diseases, including cancer.

One of the key features of KRT18P27 is its unique structure. Unlike most RNA molecules, KRT18P27 is not a linear molecule. Instead, it has a stem-loop structure that is composed of a central core and two arms, each of which is composed of a series of alternating base pairs. This unique structure has made it difficult to study, and has limited its utility as a drug target or biomarker.

However, recent studies have made progress in the characterization of KRT18P27. Researchers have identified several potential drug targets within the KRT18P27 gene, including the K181 and K182 pseudogenes, which are located upstream and downstream of the gene, respectively. These pseudogenes have been shown to be involved in the regulation of cell growth and differentiation, and have been potential targets for small molecules and other therapeutic agents.

In addition to its potential drug targets, KRT18P27 has also been shown to be a potential biomarker for various diseases. Its unique expression patterns and its involvement in the regulation of cell cycle progression have made it an attractive target for the development of diagnostic tools. For example, researchers have shown that KRT18P27 is downregulated in various cancer tissues compared to healthy tissue, and that this downregulation is associated with poor prognosis. This suggests that KRT18P27 may be a useful biomarker for the diagnosis and prognosis of cancer.

Overall, KRT18P27 is a promising candidate for drug targeting and biomarker development. Its unique structure and expression patterns make it an attractive target for researchers to study, and its potential utility as a therapeutic agent and biomarker has piqued the interest of pharmaceutical companies and researchers alike. Further studies are needed to fully understand the role of KRT18P27 in the regulation of cell growth and differentiation, and to determine its potential as a drug target and biomarker.

Protein Name: Keratin 18 Pseudogene 27

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•   protein structure and compound binding;
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•   expression level;
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•   pharmacochemistry experiments;
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More Common Targets

KRT18P28 | KRT18P29 | KRT18P31 | KRT18P33 | KRT18P34 | KRT18P4 | KRT18P40 | KRT18P41 | KRT18P42 | KRT18P44 | KRT18P48 | KRT18P49 | KRT18P5 | KRT18P50 | KRT18P51 | KRT18P55 | KRT18P59 | KRT18P6 | KRT18P62 | KRT19 | KRT19P2 | KRT19P3 | KRT2 | KRT20 | KRT222 | KRT23 | KRT24 | KRT25 | KRT26 | KRT27 | KRT28 | KRT3 | KRT31 | KRT32 | KRT33A | KRT33B | KRT34 | KRT35 | KRT36 | KRT37 | KRT38 | KRT39 | KRT4 | KRT40 | KRT42P | KRT5 | KRT6A | KRT6B | KRT6C | KRT7 | KRT7-AS | KRT71 | KRT72 | KRT73 | KRT73-AS1 | KRT74 | KRT75 | KRT76 | KRT77 | KRT78 | KRT79 | KRT8 | KRT80 | KRT81 | KRT82 | KRT83 | KRT84 | KRT85 | KRT86 | KRT87P | KRT89P | KRT8P10 | KRT8P11 | KRT8P12 | KRT8P14 | KRT8P16 | KRT8P17 | KRT8P18 | KRT8P22 | KRT8P23 | KRT8P25 | KRT8P26 | KRT8P29 | KRT8P3 | KRT8P33 | KRT8P36 | KRT8P37 | KRT8P39 | KRT8P41 | KRT8P44 | KRT8P45 | KRT8P46 | KRT8P47 | KRT8P48 | KRT8P49 | KRT8P5 | KRT8P7 | KRT8P8 | KRT8P9 | KRT9