CK14: Role in Tissue Development and Cell Signaling (G3861)

CK14: Role in Tissue Development and Cell Signaling

KRT14 (Cytokeratin 14), also known as CK14, is a protein that is expressed in a variety of tissues throughout the body. It is a member of the keratin family, which is a group of proteins that are found in the hair, nails, and skin. CK14 is one of the proteins that is associated with the growth and development of these tissues.

CK14 is also expressed in the nervous system, where it is involved in the development and maintenance of the myelin sheath that surrounds the nerve cells. It is also expressed in the heart, where it is involved in the formation of the heart muscle.

In addition to its role in cell growth and development, CK14 is also involved in the regulation of cell signaling. It has been shown to play a role in the regulation of cell proliferation, differentiation, and survival.

CK14 is also a potential drug target in the treatment of various diseases. For example, it has been shown to be involved in the development and progression of certain types of cancer, including breast and ovarian cancer. It is also involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

In addition to its potential clinical applications, CK14 is also a valuable research tool for the study of cell biology. Its expression and function can be easily isolated and characterized using various techniques, such as RNA sequencing and immunofluorescence.

Overall, CK14 is a protein that has important roles in the development and maintenance of tissues throughout the body. Its potential as a drug target and its role as a research tool make it an attractive target for further study.

Protein Name: Keratin 14

Functions: The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro

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More Common Targets

KRT15 | KRT16 | KRT16P1 | KRT16P2 | KRT16P3 | KRT16P6 | KRT17 | KRT17P1 | KRT17P2 | KRT17P3 | KRT17P5 | KRT17P7 | KRT18 | KRT18P1 | KRT18P12 | KRT18P13 | KRT18P16 | KRT18P17 | KRT18P19 | KRT18P22 | KRT18P23 | KRT18P24 | KRT18P27 | KRT18P28 | KRT18P29 | KRT18P31 | KRT18P33 | KRT18P34 | KRT18P4 | KRT18P40 | KRT18P41 | KRT18P42 | KRT18P44 | KRT18P48 | KRT18P49 | KRT18P5 | KRT18P50 | KRT18P51 | KRT18P55 | KRT18P59 | KRT18P6 | KRT18P62 | KRT19 | KRT19P2 | KRT19P3 | KRT2 | KRT20 | KRT222 | KRT23 | KRT24 | KRT25 | KRT26 | KRT27 | KRT28 | KRT3 | KRT31 | KRT32 | KRT33A | KRT33B | KRT34 | KRT35 | KRT36 | KRT37 | KRT38 | KRT39 | KRT4 | KRT40 | KRT42P | KRT5 | KRT6A | KRT6B | KRT6C | KRT7 | KRT7-AS | KRT71 | KRT72 | KRT73 | KRT73-AS1 | KRT74 | KRT75 | KRT76 | KRT77 | KRT78 | KRT79 | KRT8 | KRT80 | KRT81 | KRT82 | KRT83 | KRT84 | KRT85 | KRT86 | KRT87P | KRT89P | KRT8P10 | KRT8P11 | KRT8P12 | KRT8P14 | KRT8P16 | KRT8P17