Target Name: KRR1
NCBI ID: G11103
Review Report on KRR1 Target / Biomarker Content of Review Report on KRR1 Target / Biomarker
KRR1
Other Name(s): KRR1_HUMAN | KRR1 small subunit processome component homolog | HRB2 | HIV-1 rev binding protein 2 | Rev interacting protein | Rev-interacting protein 1 | HIV-1 Rev binding protein 2 | KRR-R motif-containing protein 1 | rev-interacting protein 1 | Rip-1 | RIP-1 | HIV-1 Rev-binding protein 2 | KRR1, small subunit (SSU) processome component, homolog

Understanding The Potential Therapeutic Applications of KRR1

KRR1 (KRR1_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, pancreas, and muscle. It is a member of the Kallikrein family of proteins, which are known for their ability to generate pyramid-like structures in various cellular compartments.

KRR1 has been identified as a potential drug target in the field of neurodegenerative diseases, due to its involvement in the regulation of cellular processes that are altered in these conditions. For example, altered levels of KRR1 have been observed in the brains of individuals with Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders.

In addition to its potential therapeutic applications, KRR1 has also been the subject of intense research in the fields of cell biology and molecular biology, as scientists seek to understand its role in these processes.

Overview of KRR1

KRR1 is a 21-kDa protein that is expressed in a variety of tissues of the human body, including the brain, pancreas, and muscle. It is a member of the Kallikrein family of proteins, which are characterized by their ability to generate pyramid- like structures in various cellular compartments.

KRR1 is composed of 118 amino acid residues and has a calculated pI of approximately 9.97. It is expressed in a variety of tissues, including the brain, pancreas, and muscle, and has been shown to be involved in the regulation of cellular processes that are Altered in neurodegenerative diseases.

Potential Therapeutic Applications

KRR1 has been identified as a potential drug target in the field of neurodegenerative diseases, due to its involvement in the regulation of cellular processes that are altered in these conditions. For example, altered levels of KRR1 have been observed in the brains of individuals with Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders.

In addition to its potential therapeutic applications, KRR1 has also been the subject of intense research in the fields of cell biology and molecular biology, as scientists seek insights to understand its role in these processes. This research has provided into the mechanisms underlying neurodegenerative diseases and has identified new potential targets for therapeutic intervention.

Studies have shown that KRR1 is involved in the regulation of several cellular processes that are altered in neurodegenerative diseases, including the regulation of angiogenesis, cell signaling, and neurotrophic signaling.

For example, studies have shown that KRR1 is involved in the regulation of angiogenesis, a process by which new blood vessels are formed in the brain. In neurodegenerative diseases, the regulation of angiogenesis is disrupted, leading to the buildup of toxic waste products and the death of brain cells.

In addition, KRR1 has also been shown to be involved in the regulation of cell signaling and neurotrophic signaling, processes that are critical for the survival and function of brain cells.

Biomarker Potential

KRR1 has also been identified as a potential biomarker for the diagnosis and monitoring of neurodegenerative diseases. This is because its levels are often altered in these conditions, making it a potentially reliable indicator of the severity and progression of these conditions.

In addition, KRR1 has been shown to be expressed in the brains of individuals with neurodegenerative diseases, providing further evidence of its potential as a biomarker for these conditions.

Conclusion

KRR1 is a protein that has been identified as a potential drug target and biomarker in the field of neurodegenerative diseases. Its involvement in the regulation of cellular processes that are altered in these conditions makes it a promising target for therapeutic intervention. Further research is needed to fully understand its role in these processes and to develop effective treatments for neurodegenerative diseases.

Protein Name: KRR1 Small Subunit Processome Component Homolog

Functions: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome

The "KRR1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRR1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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