KRT18P34: A Potential Drug Target and Biomarker (G391589)

KRT18P34: A Potential Drug Target and Biomarker

Keratin 18 (K18) pseudogene 34 (KRT18P34) is a gene that encodes a portion of the keratin protein, which is a primary component of hair, nails, and feathers. The K18 gene has been implicated in a number of diseases, including nail fungus, alopecia areata, and skin cancer. In recent years, researchers have also found that K18P34 may have potential as a drug target or biomarker.

The KRT18P34 gene is located on chromosome 18, and its encoded protein is a 21-kDa protein that is expressed in various tissues, including skin, hair, and nails. The protein is involved in a number of cellular processes, including cell adhesion, migration, and response to stimuli.

One of the unique aspects of KRT18P34 is its expression pattern. Unlike many other genes, KRT18P34 is not expressed in most tissues, but is instead expressed in the skin, hair, and nails. This allows for the potential use of small molecules or antibodies that target the protein in these specific tissues as a potential drug or biomarker.

In addition to its unique expression pattern, KRT18P34 has also been shown to play a role in a number of diseases. For example, studies have shown that K18P34 is overexpressed in a variety of skin cancers, including squamous cell carcinoma and basal cell carcinoma. This suggests that targeting the K18P34 protein may be a promising strategy for the development of new treatments for these cancers.

Another potential application of KRT18P34 is as a biomarker for the diagnosis and monitoring of skin disorders. For example, K18P34 has been shown to be overexpressed in a variety of skin conditions, including psoriasis, eczema, and dermatitis. This suggests that K18P34 may be a useful biomarker for the diagnosis and monitoring of these conditions.

In addition to its potential as a drug target or biomarker, KRT18P34 is also of interest as a potential therapeutic target for a number of other conditions. For example, K18P34 has been shown to be involved in the regulation of cell adhesion and migration, which may be relevant to a variety of conditions, including cancer, neurodegenerative diseases, and autoimmune disorders.

Overall, KRT18P34 is a protein that has significant potential as a drug target or biomarker. Its unique expression pattern and involvement in a variety of diseases make it an attractive target for research and development of new treatments. Further studies are needed to fully understand the role of KRT18P34 in these fields, and to determine its potential as a therapeutic target.

Protein Name: Keratin 18 Pseudogene 34

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•   the target screening and validation;
•   expression level;
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•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

KRT18P4 | KRT18P40 | KRT18P41 | KRT18P42 | KRT18P44 | KRT18P48 | KRT18P49 | KRT18P5 | KRT18P50 | KRT18P51 | KRT18P55 | KRT18P59 | KRT18P6 | KRT18P62 | KRT19 | KRT19P2 | KRT19P3 | KRT2 | KRT20 | KRT222 | KRT23 | KRT24 | KRT25 | KRT26 | KRT27 | KRT28 | KRT3 | KRT31 | KRT32 | KRT33A | KRT33B | KRT34 | KRT35 | KRT36 | KRT37 | KRT38 | KRT39 | KRT4 | KRT40 | KRT42P | KRT5 | KRT6A | KRT6B | KRT6C | KRT7 | KRT7-AS | KRT71 | KRT72 | KRT73 | KRT73-AS1 | KRT74 | KRT75 | KRT76 | KRT77 | KRT78 | KRT79 | KRT8 | KRT80 | KRT81 | KRT82 | KRT83 | KRT84 | KRT85 | KRT86 | KRT87P | KRT89P | KRT8P10 | KRT8P11 | KRT8P12 | KRT8P14 | KRT8P16 | KRT8P17 | KRT8P18 | KRT8P22 | KRT8P23 | KRT8P25 | KRT8P26 | KRT8P29 | KRT8P3 | KRT8P33 | KRT8P36 | KRT8P37 | KRT8P39 | KRT8P41 | KRT8P44 | KRT8P45 | KRT8P46 | KRT8P47 | KRT8P48 | KRT8P49 | KRT8P5 | KRT8P7 | KRT8P8 | KRT8P9 | KRT9 | KRT90P | KRTAP1-1 | KRTAP1-3 | KRTAP1-4 | KRTAP1-5