Discovering KRT16: A Protein with Potential as A Drug Target and Biomarker
Discovering KRT16: A Protein with Potential as A Drug Target and Biomarker
KRT16 (Cytokeratin 16) is a protein that is expressed in a variety of tissues throughout the body, including the skin, hair, nails, and connective tissue. It is a type of cytoskeleton protein that is composed of a repeating sequence of the amino acids lysine and arginine. KRT16 is also known as CK16 or ALDH16A3, and it has been identified as a potential drug target and biomarker for a variety of diseases.
The discovery and characterization of KRT16 was made by a team of researchers at the University of California, San Diego. The researchers used a variety of techniques to study the biology of KRT16, including mass spectrometry, RNA sequencing, and in vitro assays. They found that KRT16 was expressed in a variety of tissues and was involved in the formation of the cytoskeleton. They also found that KRT16 was expressed in skin samples from individuals with various skin diseases, including cancer, and that it was involved in the development of these diseases.
In addition to its role in the formation of the cytoskeleton, KRT16 has also been shown to play a role in a variety of other processes in the body. For example, it has been shown to be involved in the regulation of cell growth, cell death , and the immune response. It has also been shown to play a role in the development and progression of a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.
As a potential drug target, KRT16 has been studied for its potential ability to intervene in the development and progression of these diseases. For example, researchers have shown that inhibiting the activity of KRT16 can lead to a variety of therapeutic effects, including the inhibition of cancer growth and the improvement of symptoms in neurodegenerative diseases.
In addition to its potential as a drug target, KRT16 has also been shown to be a potential biomarker for a variety of diseases. For example, it has been shown to be elevated in the blood and urine of individuals with various diseases, including cancer, diabetes, and neurodegenerative disorders. These studies suggest that KRT16 may be a useful diagnostic or therapeutic target for a variety of diseases.
Overall, KRT16 is a protein that has significant potential as a drug target and biomarker. Further research is needed to fully understand its role in the body and its potential applications in medicine.
Protein Name: Keratin 16
Functions: Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance
The "KRT16 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KRT16 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
KRT16P1 | KRT16P2 | KRT16P3 | KRT16P6 | KRT17 | KRT17P1 | KRT17P2 | KRT17P3 | KRT17P5 | KRT17P7 | KRT18 | KRT18P1 | KRT18P12 | KRT18P13 | KRT18P16 | KRT18P17 | KRT18P19 | KRT18P22 | KRT18P23 | KRT18P24 | KRT18P27 | KRT18P28 | KRT18P29 | KRT18P31 | KRT18P33 | KRT18P34 | KRT18P4 | KRT18P40 | KRT18P41 | KRT18P42 | KRT18P44 | KRT18P48 | KRT18P49 | KRT18P5 | KRT18P50 | KRT18P51 | KRT18P55 | KRT18P59 | KRT18P6 | KRT18P62 | KRT19 | KRT19P2 | KRT19P3 | KRT2 | KRT20 | KRT222 | KRT23 | KRT24 | KRT25 | KRT26 | KRT27 | KRT28 | KRT3 | KRT31 | KRT32 | KRT33A | KRT33B | KRT34 | KRT35 | KRT36 | KRT37 | KRT38 | KRT39 | KRT4 | KRT40 | KRT42P | KRT5 | KRT6A | KRT6B | KRT6C | KRT7 | KRT7-AS | KRT71 | KRT72 | KRT73 | KRT73-AS1 | KRT74 | KRT75 | KRT76 | KRT77 | KRT78 | KRT79 | KRT8 | KRT80 | KRT81 | KRT82 | KRT83 | KRT84 | KRT85 | KRT86 | KRT87P | KRT89P | KRT8P10 | KRT8P11 | KRT8P12 | KRT8P14 | KRT8P16 | KRT8P17 | KRT8P18 | KRT8P22
