ING5: A Potential Drug Target and Biomarker (G84289)

Target Name: ING5

NCBI ID: G84289

ING5

ING5: A Potential Drug Target and Biomarker

ING5 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. Its full name is intracellular signaling gene 5, and it has been shown to play a critical role in the regulation of cellular processes that are essential for brain and tissue function. Unfortunately, ING5 has also been associated with a number of diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.

The search for new drug targets and biomarkers has led to the identification of ING5 as a promising target for drug development. In this article, we will explore the potential of ING5 as a drug target and biomarker, and discuss the scientific evidence that supports its use in these roles.

Potential Drug Target

ING5 has been shown to play a role in a number of cellular processes that are important for brain and tissue function. One of these processes is the regulation of cell survival. Studies have shown that ING5 can interact with the protein Bcl-2, which is a critical regulator of cell survival. By modulating Bcl-2 activity, ING5 has been shown to play a role in the regulation of cell survival, which is a crucial step in the development and progression of many diseases.

Another potential drug target for ING5 is its role in the regulation of cell proliferation. Studies have shown that ING5 can interact with the protein p21, which is a critical regulator of cell proliferation. By modulating p21 activity, ING5 has been shown to play a role in the regulation of cell proliferation, which is a crucial step in the development and progression of many diseases.

Potential Biomarker

ING5 has also been shown to be a potential biomarker for a number of diseases. For example, studies have shown that ING5 is overexpressed in the brains of patients with neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. This suggests that ING5 may be a useful biomarker for these disorders.

ING5 has also been shown to be overexpressed in the lungs of patients with cancer. This suggests that ING5 may be a useful biomarker for cancer, and that it may be a potential target for new anti-cancer drugs.

Conclusion

ING5 is a protein that has been shown to play a critical role in the regulation of cellular processes that are essential for brain and tissue function. Unfortunately, ING5 has also been associated with a number of diseases. The search for new drug targets and biomarkers has led to the identification of ING5 as a promising target for drug development. Based on the scientific evidence that supports its use in these roles, ING5 has the potential to be a valuable tool for the development of new treatments for a number of diseases.

Protein Name: Inhibitor Of Growth Family Member 5

Functions: Component of the HBO1 complex, which specifically mediates acetylation of histone H3 at 'Lys-14' (H3K14ac) and, to a lower extent, acetylation of histone H4 (PubMed:24065767). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (PubMed:16387653). Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator (PubMed:12750254, PubMed:16387653). Inhibits cell growth, induces a delay in S-phase progression and enhances Fas-induced apoptosis in an INCA1-dependent manner (PubMed:21750715)

The "ING5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ING5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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