Overview of PIGY: Protein Implicated in Many Diseases (G84992)

Target Name: PIGY

NCBI ID: G84992

PIGY

Overview of PIGY: Protein Implicated in Many Diseases

PIGY (Protein-Integrated Genomics Y-Box) is a protein that is expressed in various tissues and cells throughout the body. It is a key regulator of cell growth, differentiation, and survival, and is involved in many important cellular processes. PIGY has also has been implicated in several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a result, PIGY has become a promising drug target and biomarker for a variety of diseases.

PIGY is a transmembrane protein that is expressed in many different tissues, including muscle, neural crest, and epithelial cells. It is characterized by a unique protein domain that is composed of a calcification-related zinc finger, a carboxy-terminal extension, and a N-terminus. The N-terminus of PIGY contains a putative N-methylation site, which has been implicated in its stability and localization to the cytoplasm.

PIGY plays a central role in several cellular processes that are important for cell growth, differentiation, and survival. It is a key regulator of cell cycle progression, and is involved in the G1/S transition that occurs at the end of the S phase. PIGY is also involved in the regulation of cell adhesion, and is thought to play a role in the development of cancer.

In addition to its role in cell biology, PIGY is also implicated in several diseases. For example, it has been shown to be overexpressed in a variety of cancer tissues, and may be a useful biomarker for cancer diagnosis and treatment. PIGY has also been implicated in neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

PIGY has also been shown to be involved in the regulation of autoimmune diseases, including rheumatoid arthritis and multiple sclerosis. It is thought to play a role in the development of these diseases by contributing to the regulation of immune cell function and the production of autoantibodies.

In conclusion, PIGY is a protein that is expressed in a variety of tissues and cells throughout the body. It is involved in several important cellular processes and is implicated in a variety of diseases. As a result, PIGY has become a promising drug target and biomarker for a variety of diseases. Further research is needed to fully understand the role of PIGY in these diseases and to develop effective treatments.

Protein Name: Phosphatidylinositol Glycan Anchor Biosynthesis Class Y

Functions: Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis (PubMed:16162815). May act by regulating the catalytic subunit PIGA (PubMed:16162815)

The "PIGY Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PIGY comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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