PKD1: Gene Encoding Protein Involved in Cell Signaling Pathways and Tissue Maintenance

Target Name: PKD1

NCBI ID: G5310

PKD1

PKD1: Gene Encoding Protein Involved in Cell Signaling Pathways and Tissue Maintenance

PKD1 (Principally Controlled tic 1) is a gene that encodes a protein known as PKD1 (Principally Controlled tic 1). This gene is located on chromosome 18 and was first identified in 2002 as a gene that encodes a protein involved in the regulation of cell signaling pathways. PKD1 has since been shown to play a role in a wide range of physiological processes in the body, including the development and maintenance of tissues, organs, and organ systems.

One of the key functions of PKD1 is its role in the regulation of cell signaling pathways. These pathways are the complex systems that coordinate the many different functions of cells in the body, including their growth, division, and communication with one another. PKD1 is part of a family of proteins known as the TCF/PKD1 complex, which are involved in the regulation of cell signaling pathways. This family of proteins is thought to play a key role in the development and maintenance of tissues, organs, and organ systems.

PKD1 has also been shown to be involved in the regulation of cell adhesion and migration. These processes are important for the development and maintenance of tissues and organs, as well as for the formation of tissues and organs during development. PKD1 has been shown to play a key role in the regulation of cell adhesion by helping to ensure that cells stick together and form tissues. It has also been shown to play a key role in the regulation of cell migration, which is the movement of cells from one location to another in the body.

PKD1 is also involved in the regulation of cell signaling pathways that are involved in the development and maintenance of tissues and organs. For example, PKD1 has been shown to play a key role in the regulation of cell signaling pathways that are involved in the development and maintenance of tissues and organs. maintenance of the nervous system. This includes the regulation of the growth and differentiation of nerve cells, as well as the regulation of the transport of neurotransmitters across the blood-brain barrier.

In addition to its role in the regulation of cell signaling pathways, PKD1 has also been shown to play a key role in the regulation of gene expression. This is the process by which cells express the instructions for building the proteins that they need to carry out their functions. PKD1 has been shown to play a key role in the regulation of gene expression by helping to ensure that the instructions for building proteins are properly readjusted during the process of translation.

PKD1 has also been shown to play a key role in the regulation of cellular homeostasis. This is the ability of cells to maintain a stable internal environment that is free from excessive or harmful substances. PKD1 has also been shown to play a key role in the regulation of cellular homeostasis by helping to ensure that cells are able to properly remove substances from their environment that are too large or harmful to be harmful.

In conclusion, PKD1 is a gene that encodes a protein that is involved in the regulation of a wide range of physiological processes in the body. This protein plays a key role in the regulation of cell signaling pathways, cell adhesion and migration, and cellular homeostasis . As a result, PKD1 is thought to be a promising drug target and may be a valuable biomarker for a variety of diseases. Further research is needed to fully understand the role of PKD1 in the regulation of physiological processes in the body, as well as to identify potential drugs that can target this protein.

Protein Name: Polycystin 1, Transient Receptor Potential Channel Interacting

Functions: Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B (PubMed:27214281). Both PKD1 and PKD2 are required for channel activity (PubMed:27214281). Involved in renal tubulogenesis (PubMed:12482949). Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium (By similarity). Acts as a regulator of cilium length, together with PKD2 (By similarity). The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling (By similarity). The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling (By similarity). May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate interactions

The "PKD1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PKD1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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