Target Name: PIRAT1
NCBI ID: G101929559
Review Report on PIRAT1 Target / Biomarker Content of Review Report on PIRAT1 Target / Biomarker
PIRAT1
Other Name(s): PIRAT1 variant 1 | PU.1 (SP1) induced regulator of S100A8 and S100A9 alarmin transcription 1, transcript variant 1 | PIRAT | PU.1 (SP1) induced regulator of S100A8 and S100A9 alarmin transcription 1 | LINC00211 | NCRNA00211

Pirat1: A Potential Drug Target and Biomarker for Various Diseases

Pirat1, a gene encoding a protein involved in the intracellular signaling pathway known as the intercellular signaling pathway (ICSP), has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. TheICSP is a critical pathway involved in cell signaling, cell adhesion, and cell survival, and is implicated in the development and progression of many diseases. Therefore, targeting the Pirat1 protein has the potential to provide new insights into the pathogenesis of these diseases and may lead to the development of new treatments.

Pirat1 function and localization

Pirat1 is a 21-kDa protein that is expressed in various tissues and cells, including brain, spinal cord, muscle, heart, and cancer cells. It is primarily localized to the endoplasmic reticulum (ER) and cytoplasm, and is also detected in the cell surface. Pirat1 is involved in the regulation of several intracellular signaling pathways, including the NF-kappa pathway, the PI3K/Akt pathway, and the NF-kappa-B pathway.

Pirat1 plays a crucial role in the regulation of cell adhesion and migration. It is involved in the formation of tight junctions, which are critical for maintaining tissue structure and function, and in the regulation of cell migration. Additionally, Pirat1 is involved in the regulation of cell survival, as it has been shown to play a role in the apoptosis-mediated regulation of cell survival.

Pirat1 is also involved in the regulation of neurotransmitter signaling, including the regulation of synaptic plasticity and the modulation of neurotransmitter release. It has been shown to play a role in the regulation of neurotransmitter release in response to different types of neurotransmitters, including dopamine, GABA, and serotonin.

Pirat1 as a potential drug target

The potential of Pirat1 as a drug target is based on its involvement in multiple intracellular signaling pathways and its role in the regulation of cell adhesion, migration, and neurotransmission. Several studies have shown that targeting the Pirat1 protein has the potential to treat various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

In cancer, Pirat1 has been shown to be involved in the regulation of cell adhesion and migration, which are critical for the development and progression of cancer. Therefore, targeting the Pirat1 protein has the potential to be a useful cancer therapeutic. Additionally, Pirat1 has been shown to play a role in the regulation of neurotransmission, which is implicated in the development and progression of neurodegenerative diseases. Therefore, targeting the Pirat1 protein may also be a useful approach for the treatment of neurodegenerative diseases.

In neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, Pirat1 has been shown to be involved in the regulation of neurotransmission and cell survival. Therefore, targeting the Pirat1 protein may have the potential to be a useful approach for the treatment of these diseases.

In autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis, Pirat1 has been shown to be involved in the regulation of immune cell function and the regulation of inflammation. Therefore, targeting the Pirat1 protein may have the potential to be a useful approach for the treatment of autoimmune disorders.

Conclusion

Pirat1 is a protein that is involved in multiple intracellular signaling pathways and plays a crucial role in the regulation of cell adhesion, migration, and neurotransmission. Based on its involvement in these processes, Pirat1 has the potential to be a drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to fully understand the role of Pirat1 in these diseases and to develop effective treatments based on its potential as a drug target and biomarker.

Protein Name: PU.1 (SP1) Induced Regulator Of S100A8 And S100A9 Alarmin Transcription 1

The "PIRAT1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PIRAT1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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