PLRs: Non-coding RNAs Regulating Gene Silencing in Plants (G440822)

Target Name: PIWIL3

NCBI ID: G440822

PIWIL3

PLRs: Non-coding RNAs Regulating Gene Silencing in Plants

Piwi-like RNA-mediated gene silencing (PIWIL3) is a non-coding RNA (ncRNA) that plays a crucial role in gene regulation in plants. It is a member of the Piwi-like RNA (PLR) family, which are known for their ability to interact with the protein Piwi, a key regulator of gene silencing in plants.

Gene silencing is a crucial mechanism of plant development and growth. It is the process by which cells turn off gene expression when they are not needed, such as when the plant is dormant or stressed. This helps to reduce the amount of gene expression and reduce the risk of over-expression of potentially harmful genes.

PLRs are a family of non-coding RNAs that have been identified as key regulators of gene silencing in plants. They are characterized by the presence of a specific RNA structure, known as a PLR-like domain, which is responsible for their unique function. PLRs interact with the protein Piwi, which is a key regulator of gene silencing in plants.

In recent years, the study of PLRs has gained significant interest due to their potential as drug targets or biomarkers. The ability of PLRs to regulate gene expression in a specific and targeted manner makes them an attractive target for drug development. Additionally, their role in gene regulation makes them a valuable tool for the study of plant development and growth.

One of the key functions of PLRs is their ability to mediate gene silencing. This is done through the formation of a complex with Piwi, which results in the recruitment of the RNA-protein complex to the nuclear kernel, where it can interact with the protein responsible for silencing gene expression. This interaction between PLRs and Piwi is critical for the regulation of gene expression in plants.

PLRs have been shown to play a role in a wide range of plant processes, including growth, development, and response to environmental stimuli. They have also been shown to be involved in the regulation of gene expression in response to factors such as light, temperature , and water availability.

In addition to their role in gene regulation, PLRs have also been shown to be involved in the regulation of gene expression in response to environmental stimuli. For example, studies have shown that PLRs can play a role in the regulation of gene expression in response to light intensity, with increased light intensity leading to increased levels of gene expression.

Another function of PLRs is their ability to interact with other non-coding RNAs, such as small nucleolar RNA (snRNA), in order to regulate gene expression. This interaction between PLRs and other non-coding RNAs allows for the precise regulation of gene expression in plants.

PLRs have also been shown to play a role in the regulation of gene expression in response to temperature and water availability. For example, studies have shown that increased temperature and decreased water availability can both cause changes in the levels of gene expression in PLRs.

In conclusion, Piwi-like RNA-mediated gene silencing (PIWIL3) is a non-coding RNA that plays a crucial role in the regulation of gene expression in plants. It is a member of the Piwi-like RNA family and interacts with the protein Piwi, which is responsible for the regulation of gene silencing in plants. PLRs have been shown to play a role in a wide range of plant processes, including growth, development, and response to environmental stimuli. They are also involved in the regulation of gene expression in response to factors such as light, temperature, and water availability. As a result, PLRs make an attractive target for drug development and have the potential to be used as biomarkers for a wide range of plant-related conditions.

Protein Name: Piwi Like RNA-mediated Gene Silencing 3

Functions: May play a role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation (By similarity)

The "PIWIL3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PIWIL3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets