PISRT1: A Potential Drug Target and Biomarker for Various Diseases

Target Name: PISRT1

NCBI ID: G140464

PISRT1

Other Name(s): NCRNA00195 | PISRT1 lncRNA

PISRT1: A Potential Drug Target and Biomarker for Various Diseases

PISRT1 (Proteasome-Derived Size-Adaptable RNA-Binding protein T domain interacting RNA binding domain) is a protein that plays a crucial role in cellular processes such as cell growth, apoptosis, and translation of RNA into protein. PISRT1 has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and chronic obstructive pulmonary disease (COPD).

PISRT1 Structure and Function

PISRT1 is a 21 kDa protein that is composed of an N-terminal transmembrane region, a cytoplasmic domain, and an C-terminal protein domain. The N-terminal region contains a nucleotide-binding oligomerization domain (NBO domain), which consists of a nucleotide-binding domain and a domain that interacts with the RNA-binding domain. The C-terminal region contains a structural domain (SD) that contains a unique farnesylated cysteine 鈥嬧?媟esidue, which is important for protein-protein interaction and may contribute to the stability of the protein.

PISRT1 functions as an RNA-binding protein by interacting with small, 28-nt RNAs. The NBO domain is responsible for binding to the RNA, while the SD domain interacts with the protein to modulate the structure and stability of the complex. PISRT1 has been shown to interact with various RNA species, including microRNAs, snRNAs, and rRNAs.

PISRT1 is involved in a variety of cellular processes, including cell growth, apoptosis, and translation of RNA into protein. PISRT1 has been shown to be involved in the regulation of cell cycle progression, apoptosis, and cell survival. For example, PISRT1 has been shown to be involved in the regulation of cell apoptosis, as it has been shown to induce cell apoptosis in various cell types.

PISRT1 has also been shown to be involved in the regulation of translation of RNA into protein. It has been shown to interact with various translation factors, including factors that regulate the initiation of translation and the stability of the translation complex.

PISRT1 as a Drug Target

PISRT1 has been identified as a potential drug target due to its involvement in various cellular processes that are implicated in the development and progression of various diseases. PISRT1 has been shown to be involved in the regulation of cell apoptosis, cell cycle progression, and translation of RNA into protein, all of which are implicated in the development and progression of various diseases, including cancer, neurodegenerative diseases, and COPD.

PISRT1 has also been shown to be a good candidate for targeting small RNA-protein interactions, as it has been shown to interact with various small RNAs. This suggests that PISRT1 may be a useful target for small RNA-protein interactions, which are a rapidly growing area of 鈥嬧?媟esearch in the field of nanotechnology and biotechnology.

PISRT1 as a Biomarker

PISRT1 has also been identified as a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and COPD. PISRT1 has been shown to be expressed in a variety of tissues and cells, including cancer cells, neurodegenerative disease cells, and airway epithelial cells, which makes it a potential biomarker for these diseases.

PISRT1 has also been shown to be involved in the regulation of various cellular processes that are implicated in the development and progression of these diseases. For example, PISRT1 has been shown to be involved in the regulation of cell apoptosis, which is implicated in the development and progression of cancer. It has also been shown to be involved in

Protein Name: PISRT1 LncRNA

The "PISRT1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PISRT1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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