Implications of LAMTOR3 in Cellular Signaling and Tissue Development

Target Name: LAMTOR3

NCBI ID: G8649

LAMTOR3

Implications of LAMTOR3 in Cellular Signaling and Tissue Development

LAMTOR3 (MEK-binding partner 1) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and skeletal muscles. It is a member of the LAMTOR family of proteins, which are known for their role in intracellular signaling pathways. LAMTOR3 is highly conserved and has a similar structure to other LAMTORs.

The LAMTOR3 protein is composed of 215 amino acid residues and has a calculated molecular mass of 29.9 kDa. It has a single transmembrane region and a N-terminus that is involved in protein-protein interactions. The protein also has a C-terminus that is involved in binding to the protein MEK-1 (MAPK/ERK signaling pathway).

LAMTOR3 is a protein that has been implicated in various cellular processes, including cell signaling, cell adhesion, and muscle contraction. It is a key regulator of the MAPK/ERK signaling pathway, which is involved in various cellular processes, including cell proliferation, differentiation , and survival.

Research has suggested that LAMTOR3 may be a drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and muscle-related conditions. LAMTOR3 has been shown to be involved in the regulation of cell proliferation, differentiation, and survival, which may make it a useful target for drugs that are designed to inhibit these processes.

In addition to its involvement in the MAPK/ERK signaling pathway, LAMTOR3 has also been shown to be involved in the regulation of several other signaling pathways, including the PI3K/AKT signaling pathway and the TGF-β signaling pathway. These signaling pathways are involved in various cellular processes, including cell survival, angiogenesis, and tissue repair.

LAMTOR3 has also been shown to be involved in the regulation of cellular adhesion, which is the process by which cells stick to the surface of other cells. This process is important for the development and maintenance of tissues and organs, including tissues used in transplantation.

In addition to its role in cellular signaling, LAMTOR3 has also been shown to play a role in the regulation of cellular interactions with other proteins. It is a protein that can interact with the protein MEK-1, which is involved in the MAPK/ERK signaling pathway. This interaction between LAMTOR3 and MEK-1 may be important for the regulation of cellular processes that involve the MAPK/ERK signaling pathway.

Overall, LAMTOR3 is a protein that has been shown to be involved in various cellular processes that are important for the development and maintenance of tissues and organs. Its involvement in the regulation of the MAPK/ERK and PI3K/AKT signaling pathways, as well as its involvement in cellular adhesion, makes it a potential drug target or biomarker for various diseases. Further research is needed to fully understand the role of LAMTOR3 in these processes and to develop effective treatments for diseases that are caused by the disruption of these processes.

Protein Name: Late Endosomal/lysosomal Adaptor, MAPK And MTOR Activator 3

Functions: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2

The "LAMTOR3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LAMTOR3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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