PLXNA4: A Protein Involved in Tissue Development, Growth and Response To Stimuli

Target Name: PLXNA4

NCBI ID: G91584

PLXNA4

PLXNA4: A Protein Involved in Tissue Development, Growth and Response To Stimuli

PLXNA4, also known as Plexin A4, is a protein that is expressed in most tissues of the body. It is a member of the Plexin family, which is a family of transmembrane proteins that play a critical role in the transport of various molecules across cell membranes. One of the functions of PLXNA4 is to transport the protein PDGF-BB, which is a key signaling molecule that plays a role in the development, maintenance, and regression of tissues.

PLXNA4 is also known as transcript variant 1, which means that it is one of several possible variants of the PLXNA4 gene. These variants may differ in their structure or function, and research has shown that some of these variants can be altered in various diseases, including cancer.

The search for potential drug targets and biomarkers is an important part of modern medicine, and PLXNA4 is an attractive candidate for both. Several studies have shown that PLXNA4 is involved in various cellular processes that are important for human health, including the development and maintenance of tissues, the regulation of cell growth and division, and the response to external stimuli.

One of the key features of PLXNA4 is its role in the development and maintenance of tissues. PLXNA4 is a transmembrane protein that is involved in the delivery of various signaling molecules to the cell surface. These molecules include PDGF-BB, which is a key regulator of cell growth and development. PLXNA4 is also involved in the delivery of other signaling molecules, including Wnt, which is a molecule that is important for the development and maintenance of tissues.

In addition to its role in tissue development and maintenance, PLXNA4 is also involved in the regulation of cell growth and division. It is a transcription factor that is involved in the regulation of gene expression, and has been shown to play a role in the regulation of cell cycle progression. PLXNA4 has also been shown to play a role in the regulation of cell division, and is involved in the establishment of the G1/S transition, which is a critical step in the cell cycle.

PLXNA4 is also involved in the regulation of cellular responses to external stimuli. It is a receptor for various signaling molecules, including PDGF-BB, which is a key regulator of cell growth and development. PLXNA4 is also involved in the regulation of cellular responses to mechanical and chemical stimuli, and has been shown to play a role in the regulation of pain perception.

In conclusion, PLXNA4 is a protein that is involved in various cellular processes that are important for human health. Its role in tissue development and maintenance, as well as its involvement in the regulation of cell growth and division, make it an attractive candidate for drug targets or biomarkers. Further research is needed to fully understand the functions of PLXNA4 and its potential as a drug or biomarker.

Protein Name: Plexin A4

Functions: Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity)

The "PLXNA4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PLXNA4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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